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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRPF6
All Species:
48.48
Human Site:
S279
Identified Species:
88.89
UniProt:
O94906
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O94906
NP_036601.2
941
106925
S279
G
Y
L
T
D
L
N
S
M
I
P
T
H
G
G
Chimpanzee
Pan troglodytes
XP_001152053
941
106833
S279
G
Y
L
T
D
L
N
S
M
I
P
T
H
G
G
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_534481
1000
112841
S338
G
Y
L
T
D
L
N
S
M
I
P
T
H
G
G
Cat
Felis silvestris
Mouse
Mus musculus
Q91YR7
941
106703
S279
G
Y
L
T
D
L
N
S
M
I
P
T
H
G
G
Rat
Rattus norvegicus
NP_001073234
941
106745
S279
G
Y
L
T
D
L
N
S
M
I
P
T
H
G
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507659
1026
115336
S364
G
Y
L
T
D
L
N
S
M
I
P
T
H
G
G
Chicken
Gallus gallus
XP_417426
941
106786
S279
G
Y
L
T
D
L
N
S
M
I
P
T
H
G
G
Frog
Xenopus laevis
NP_001087374
948
107315
S286
G
Y
L
T
D
L
N
S
M
I
P
T
H
G
G
Zebra Danio
Brachydanio rerio
NP_997820
944
106866
S282
G
Y
L
T
D
L
N
S
M
I
P
T
Y
G
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649073
931
105209
S269
G
Y
L
T
D
L
Q
S
M
I
P
T
Y
G
G
Honey Bee
Apis mellifera
XP_623891
931
105090
S268
G
Y
L
T
D
L
Q
S
M
I
P
T
Y
G
G
Nematode Worm
Caenorhab. elegans
NP_507525
968
109143
S305
G
Y
L
T
D
M
Q
S
I
I
P
Q
M
G
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P19735
899
104211
Q269
K
I
I
E
N
G
C
Q
E
C
P
R
S
S
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
N.A.
91.9
N.A.
98.3
98.1
N.A.
89.3
97.2
94.4
91.8
N.A.
71.7
73.5
55.1
N.A.
Protein Similarity:
100
99.6
N.A.
93.5
N.A.
99.2
99.2
N.A.
90.7
98.8
97.1
95.5
N.A.
84.8
86
71.6
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
100
100
100
93.3
N.A.
86.6
86.6
66.6
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
93.3
93.3
80
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
28.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
48.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
8
0
0
8
0
0
0
0
0
% C
% Asp:
0
0
0
0
93
0
0
0
0
0
0
0
0
0
8
% D
% Glu:
0
0
0
8
0
0
0
0
8
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
93
0
0
0
0
8
0
0
0
0
0
0
0
93
93
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
62
0
0
% H
% Ile:
0
8
8
0
0
0
0
0
8
93
0
0
0
0
0
% I
% Lys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
93
0
0
85
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
8
0
0
85
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
8
0
70
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
100
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
24
8
0
0
0
8
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
93
0
0
0
0
8
8
0
% S
% Thr:
0
0
0
93
0
0
0
0
0
0
0
85
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
93
0
0
0
0
0
0
0
0
0
0
24
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _