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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRPF6
All Species:
37.58
Human Site:
S783
Identified Species:
68.89
UniProt:
O94906
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O94906
NP_036601.2
941
106925
S783
N
P
G
L
W
L
E
S
V
R
L
E
Y
R
A
Chimpanzee
Pan troglodytes
XP_001152053
941
106833
S783
N
P
G
L
W
L
E
S
V
R
L
E
Y
R
A
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_534481
1000
112841
S842
N
P
G
L
W
L
E
S
V
R
L
E
Y
R
A
Cat
Felis silvestris
Mouse
Mus musculus
Q91YR7
941
106703
S783
N
P
G
L
W
L
E
S
V
R
L
E
Y
R
A
Rat
Rattus norvegicus
NP_001073234
941
106745
S783
N
P
G
L
W
L
E
S
V
R
L
E
Y
R
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507659
1026
115336
S868
N
P
D
L
W
L
E
S
V
R
L
E
Y
R
A
Chicken
Gallus gallus
XP_417426
941
106786
S783
N
A
D
L
W
L
E
S
V
R
L
E
Y
R
A
Frog
Xenopus laevis
NP_001087374
948
107315
S790
T
P
E
L
W
L
E
S
V
R
L
E
F
R
A
Zebra Danio
Brachydanio rerio
NP_997820
944
106866
S786
S
P
E
L
W
L
E
S
V
R
L
E
Y
R
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649073
931
105209
A773
V
A
V
L
W
L
E
A
I
R
V
E
L
R
A
Honey Bee
Apis mellifera
XP_623891
931
105090
A772
N
P
E
L
W
L
E
A
I
R
N
E
L
K
I
Nematode Worm
Caenorhab. elegans
NP_507525
968
109143
S810
N
D
D
L
W
L
E
S
V
R
F
E
Q
R
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P19735
899
104211
K743
D
V
L
F
Y
I
A
K
I
Q
M
E
I
R
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
N.A.
91.9
N.A.
98.3
98.1
N.A.
89.3
97.2
94.4
91.8
N.A.
71.7
73.5
55.1
N.A.
Protein Similarity:
100
99.6
N.A.
93.5
N.A.
99.2
99.2
N.A.
90.7
98.8
97.1
95.5
N.A.
84.8
86
71.6
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
93.3
86.6
80
86.6
N.A.
53.3
53.3
66.6
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
93.3
86.6
86.6
93.3
N.A.
73.3
73.3
66.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
28.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
48.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
0
0
0
0
8
16
0
0
0
0
0
0
77
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
24
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
24
0
0
0
93
0
0
0
0
100
0
0
0
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
8
0
8
0
0
% F
% Gly:
0
0
39
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
8
0
0
24
0
0
0
8
0
8
% I
% Lys:
0
0
0
0
0
0
0
8
0
0
0
0
0
8
0
% K
% Leu:
0
0
8
93
0
93
0
0
0
0
70
0
16
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
70
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% N
% Pro:
0
70
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
8
0
0
8
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
93
0
0
0
93
0
% R
% Ser:
8
0
0
0
0
0
0
77
0
0
0
0
0
0
0
% S
% Thr:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
8
8
8
0
0
0
0
0
77
0
8
0
0
0
8
% V
% Trp:
0
0
0
0
93
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
0
0
0
0
62
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _