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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRPF6
All Species:
43.94
Human Site:
S87
Identified Species:
80.56
UniProt:
O94906
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O94906
NP_036601.2
941
106925
S87
E
F
N
G
Y
A
G
S
L
F
S
S
G
P
Y
Chimpanzee
Pan troglodytes
XP_001152053
941
106833
S87
E
F
N
G
Y
A
G
S
L
F
S
S
G
P
Y
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_534481
1000
112841
S146
E
F
N
G
Y
A
G
S
L
F
S
S
G
P
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q91YR7
941
106703
S87
E
F
N
G
Y
A
G
S
L
F
S
S
G
P
Y
Rat
Rattus norvegicus
NP_001073234
941
106745
S87
E
F
N
G
Y
A
G
S
L
F
S
S
G
P
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507659
1026
115336
S172
E
F
N
G
Y
A
G
S
L
F
S
S
G
P
Y
Chicken
Gallus gallus
XP_417426
941
106786
S87
E
F
N
G
Y
A
G
S
L
F
S
S
G
P
Y
Frog
Xenopus laevis
NP_001087374
948
107315
S94
E
F
N
G
Y
A
G
S
L
F
S
S
G
P
Y
Zebra Danio
Brachydanio rerio
NP_997820
944
106866
S95
E
F
N
G
Y
A
G
S
L
F
S
S
G
P
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649073
931
105209
Y88
N
Y
D
E
F
S
G
Y
S
G
S
L
F
S
K
Honey Bee
Apis mellifera
XP_623891
931
105090
Y87
N
Y
D
E
F
S
G
Y
G
G
S
L
F
S
K
Nematode Worm
Caenorhab. elegans
NP_507525
968
109143
S100
E
F
S
G
Y
S
G
S
L
F
S
K
D
P
Y
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P19735
899
104211
A79
K
T
L
E
L
K
L
A
Q
K
K
K
K
R
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
N.A.
91.9
N.A.
98.3
98.1
N.A.
89.3
97.2
94.4
91.8
N.A.
71.7
73.5
55.1
N.A.
Protein Similarity:
100
99.6
N.A.
93.5
N.A.
99.2
99.2
N.A.
90.7
98.8
97.1
95.5
N.A.
84.8
86
71.6
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
13.3
13.3
73.3
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
40
40
86.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
28.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
48.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
70
0
8
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
16
0
0
0
0
0
0
0
0
0
8
0
0
% D
% Glu:
77
0
0
24
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
77
0
0
16
0
0
0
0
77
0
0
16
0
0
% F
% Gly:
0
0
0
77
0
0
93
0
8
16
0
0
70
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
8
0
0
0
0
8
0
0
0
8
8
16
8
0
16
% K
% Leu:
0
0
8
0
8
0
8
0
77
0
0
16
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
16
0
70
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
77
0
% P
% Gln:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% R
% Ser:
0
0
8
0
0
24
0
77
8
0
93
70
0
16
0
% S
% Thr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
16
0
0
77
0
0
16
0
0
0
0
0
0
77
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _