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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRPF6
All Species:
45.15
Human Site:
Y582
Identified Species:
82.78
UniProt:
O94906
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O94906
NP_036601.2
941
106925
Y582
S
V
W
L
R
A
A
Y
F
E
K
N
H
G
T
Chimpanzee
Pan troglodytes
XP_001152053
941
106833
Y582
S
V
W
L
R
A
A
Y
F
E
K
N
H
G
T
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_534481
1000
112841
Y641
S
V
W
L
R
A
A
Y
F
E
K
N
H
G
T
Cat
Felis silvestris
Mouse
Mus musculus
Q91YR7
941
106703
Y582
S
V
W
L
R
A
A
Y
F
E
K
N
H
G
T
Rat
Rattus norvegicus
NP_001073234
941
106745
Y582
S
V
W
L
R
A
A
Y
F
E
K
N
H
G
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507659
1026
115336
Y667
S
V
W
L
R
A
A
Y
F
E
K
N
H
G
T
Chicken
Gallus gallus
XP_417426
941
106786
Y582
S
V
W
L
R
A
A
Y
F
E
K
N
H
G
T
Frog
Xenopus laevis
NP_001087374
948
107315
Y589
S
V
W
L
R
A
A
Y
F
E
K
N
H
G
T
Zebra Danio
Brachydanio rerio
NP_997820
944
106866
Y585
S
V
W
L
R
A
A
Y
F
E
K
N
N
G
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649073
931
105209
Y572
S
I
W
L
R
A
A
Y
F
E
K
N
H
G
T
Honey Bee
Apis mellifera
XP_623891
931
105090
Y571
S
I
W
L
R
A
A
Y
F
E
K
T
Y
G
T
Nematode Worm
Caenorhab. elegans
NP_507525
968
109143
H608
S
I
W
D
A
A
I
H
F
E
R
E
H
G
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P19735
899
104211
M553
S
D
D
I
R
A
N
M
R
E
K
S
P
G
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
N.A.
91.9
N.A.
98.3
98.1
N.A.
89.3
97.2
94.4
91.8
N.A.
71.7
73.5
55.1
N.A.
Protein Similarity:
100
99.6
N.A.
93.5
N.A.
99.2
99.2
N.A.
90.7
98.8
97.1
95.5
N.A.
84.8
86
71.6
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
100
100
100
93.3
N.A.
93.3
80
46.6
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
100
93.3
73.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
28.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
48.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
100
85
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
8
8
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
100
0
8
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
93
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
100
0
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
77
0
0
% H
% Ile:
0
24
0
8
0
0
8
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
93
0
0
0
0
% K
% Leu:
0
0
0
85
0
0
0
0
0
0
0
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
8
0
0
0
0
77
8
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
93
0
0
0
8
0
8
0
0
0
0
% R
% Ser:
100
0
0
0
0
0
0
0
0
0
0
8
0
0
8
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
85
% T
% Val:
0
70
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
93
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
85
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _