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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCA8
All Species:
20
Human Site:
S241
Identified Species:
44
UniProt:
O94911
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O94911
NP_009099.1
1581
179245
S241
S
S
F
I
Y
Y
A
S
V
N
V
T
R
E
R
Chimpanzee
Pan troglodytes
XP_001165971
1581
179231
S241
S
S
F
I
Y
Y
A
S
V
N
V
T
R
E
R
Rhesus Macaque
Macaca mulatta
XP_001082492
1581
179168
S241
S
P
F
I
Y
Y
A
S
V
N
V
T
R
E
R
Dog
Lupus familis
XP_548020
1622
184532
S241
S
S
F
T
Y
Y
A
S
I
N
V
T
R
E
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8K440
1620
183021
S240
S
P
I
T
Y
Y
V
S
I
N
V
A
R
E
R
Rat
Rattus norvegicus
Q8CF82
1642
185792
A237
S
P
F
G
Y
F
L
A
I
H
I
V
A
E
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509469
1722
195635
A317
S
P
F
G
Y
Y
L
A
I
H
I
V
A
E
K
Chicken
Gallus gallus
XP_415691
1546
175373
S230
M
A
F
W
L
S
W
S
L
L
Y
A
I
Y
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001092716
1654
185619
V238
P
F
V
S
F
L
I
V
N
V
A
A
E
K
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34358
1704
191394
T277
F
I
N
V
I
H
I
T
R
E
I
A
A
E
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84M24
1882
209045
S296
F
P
I
S
R
L
I
S
Y
S
V
F
E
K
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
96.7
77.1
N.A.
73.5
40.3
N.A.
39.4
46.1
N.A.
42.4
N.A.
N.A.
N.A.
22
N.A.
Protein Similarity:
100
99.5
97.9
85.4
N.A.
83.5
60.1
N.A.
59
63.5
N.A.
60.8
N.A.
N.A.
N.A.
41.2
N.A.
P-Site Identity:
100
100
93.3
86.6
N.A.
60
26.6
N.A.
33.3
13.3
N.A.
0
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
100
93.3
93.3
N.A.
66.6
66.6
N.A.
66.6
26.6
N.A.
13.3
N.A.
N.A.
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.3
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
37
19
0
0
10
37
28
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
10
0
0
19
73
19
% E
% Phe:
19
10
64
0
10
10
0
0
0
0
0
10
0
0
0
% F
% Gly:
0
0
0
19
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
10
0
0
0
19
0
0
0
0
0
% H
% Ile:
0
10
19
28
10
0
28
0
37
0
28
0
10
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
19
19
% K
% Leu:
0
0
0
0
10
19
19
0
10
10
0
0
0
0
0
% L
% Met:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
0
10
46
0
0
0
0
10
% N
% Pro:
10
46
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
10
0
0
0
10
0
0
0
46
0
46
% R
% Ser:
64
28
0
19
0
10
0
64
0
10
0
0
0
0
0
% S
% Thr:
0
0
0
19
0
0
0
10
0
0
0
37
0
0
0
% T
% Val:
0
0
10
10
0
0
10
10
28
10
55
19
0
0
10
% V
% Trp:
0
0
0
10
0
0
10
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
64
55
0
0
10
0
10
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _