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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCA8
All Species:
31.21
Human Site:
S440
Identified Species:
68.67
UniProt:
O94911
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O94911
NP_009099.1
1581
179245
S440
P
L
F
F
L
K
S
S
F
W
S
Q
T
Q
K
Chimpanzee
Pan troglodytes
XP_001165971
1581
179231
S440
P
L
F
F
L
K
S
S
F
W
S
Q
T
Q
K
Rhesus Macaque
Macaca mulatta
XP_001082492
1581
179168
S440
P
L
F
F
L
K
S
S
F
W
S
Q
T
Q
K
Dog
Lupus familis
XP_548020
1622
184532
S440
P
L
F
F
L
K
P
S
F
W
S
R
Q
H
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8K440
1620
183021
S439
P
L
F
F
L
K
S
S
F
W
L
Q
T
R
K
Rat
Rattus norvegicus
Q8CF82
1642
185792
S438
S
L
Y
F
L
K
P
S
Y
W
S
K
N
K
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509469
1722
195635
S518
S
L
Y
F
M
Q
P
S
Y
W
S
K
N
K
R
Chicken
Gallus gallus
XP_415691
1546
175373
T430
R
L
H
N
I
K
K
T
Y
K
K
K
D
K
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001092716
1654
185619
S438
V
L
Y
F
L
K
P
S
Y
W
S
K
R
R
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34358
1704
191394
D484
E
D
D
E
N
Q
T
D
G
V
T
A
Q
N
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84M24
1882
209045
Y496
W
N
F
I
F
S
K
Y
F
G
R
K
K
N
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
96.7
77.1
N.A.
73.5
40.3
N.A.
39.4
46.1
N.A.
42.4
N.A.
N.A.
N.A.
22
N.A.
Protein Similarity:
100
99.5
97.9
85.4
N.A.
83.5
60.1
N.A.
59
63.5
N.A.
60.8
N.A.
N.A.
N.A.
41.2
N.A.
P-Site Identity:
100
100
100
73.3
N.A.
86.6
46.6
N.A.
33.3
20
N.A.
53.3
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
100
100
80
N.A.
93.3
80
N.A.
80
53.3
N.A.
80
N.A.
N.A.
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.3
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
10
0
0
0
0
10
0
0
0
0
10
0
0
% D
% Glu:
10
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
55
73
10
0
0
0
55
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
10
10
0
0
0
0
0
% G
% His:
0
0
10
0
0
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
0
0
0
10
10
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
73
19
0
0
10
10
46
10
28
64
% K
% Leu:
0
82
0
0
64
0
0
0
0
0
10
0
0
0
0
% L
% Met:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
10
10
0
0
0
0
0
0
0
19
19
10
% N
% Pro:
46
0
0
0
0
0
37
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
19
0
0
0
0
0
37
19
28
0
% Q
% Arg:
10
0
0
0
0
0
0
0
0
0
10
10
10
19
19
% R
% Ser:
19
0
0
0
0
10
37
73
0
0
64
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
10
10
0
0
10
0
37
0
10
% T
% Val:
10
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% V
% Trp:
10
0
0
0
0
0
0
0
0
73
0
0
0
0
0
% W
% Tyr:
0
0
28
0
0
0
0
10
37
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _