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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABCA8 All Species: 22.42
Human Site: T794 Identified Species: 49.33
UniProt: O94911 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O94911 NP_009099.1 1581 179245 T794 S L N K M R K T I G G V A L W
Chimpanzee Pan troglodytes XP_001165971 1581 179231 T794 S L N K M R K T I G G V A L W
Rhesus Macaque Macaca mulatta XP_001082492 1581 179168 T794 S L N K M R K T I G G V A L W
Dog Lupus familis XP_548020 1622 184532 T834 S L N E M R T T L G G M A L W
Cat Felis silvestris
Mouse Mus musculus Q8K440 1620 183021 T833 S L R E T E K T D G M A L W R
Rat Rattus norvegicus Q8CF82 1642 185792 S832 I L S E T K A S L V S T M S L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509469 1722 195635 S912 I L S E T K S S A V S T M A L
Chicken Gallus gallus XP_415691 1546 175373 W780 T L S S W A L W R Q Q V S A M
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001092716 1654 185619 T836 F S D S R Q D T V T G H A L W
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34358 1704 191394 K906 N A S E P S L K P A G Y D T Q
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q84M24 1882 209045 S905 C I G S N Q K S S M Q P K L L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 96.7 77.1 N.A. 73.5 40.3 N.A. 39.4 46.1 N.A. 42.4 N.A. N.A. N.A. 22 N.A.
Protein Similarity: 100 99.5 97.9 85.4 N.A. 83.5 60.1 N.A. 59 63.5 N.A. 60.8 N.A. N.A. N.A. 41.2 N.A.
P-Site Identity: 100 100 100 73.3 N.A. 33.3 6.6 N.A. 6.6 13.3 N.A. 33.3 N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 40 40 N.A. 33.3 33.3 N.A. 53.3 N.A. N.A. N.A. 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 24.6 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 43.3 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 0 10 10 0 10 10 0 10 46 19 0 % A
% Cys: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 0 0 0 10 0 10 0 0 0 10 0 0 % D
% Glu: 0 0 0 46 0 10 0 0 0 0 0 0 0 0 0 % E
% Phe: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 10 0 0 0 0 0 0 46 55 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % H
% Ile: 19 10 0 0 0 0 0 0 28 0 0 0 0 0 0 % I
% Lys: 0 0 0 28 0 19 46 10 0 0 0 0 10 0 0 % K
% Leu: 0 73 0 0 0 0 19 0 19 0 0 0 10 55 28 % L
% Met: 0 0 0 0 37 0 0 0 0 10 10 10 19 0 10 % M
% Asn: 10 0 37 0 10 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 10 0 0 0 10 0 0 10 0 0 0 % P
% Gln: 0 0 0 0 0 19 0 0 0 10 19 0 0 0 10 % Q
% Arg: 0 0 10 0 10 37 0 0 10 0 0 0 0 0 10 % R
% Ser: 46 10 37 28 0 10 10 28 10 0 19 0 10 10 0 % S
% Thr: 10 0 0 0 28 0 10 55 0 10 0 19 0 10 0 % T
% Val: 0 0 0 0 0 0 0 0 10 19 0 37 0 0 0 % V
% Trp: 0 0 0 0 10 0 0 10 0 0 0 0 0 10 46 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _