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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCA8
All Species:
9.09
Human Site:
Y728
Identified Species:
20
UniProt:
O94911
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O94911
NP_009099.1
1581
179245
Y728
L
Y
K
D
L
D
S
Y
P
D
L
G
I
E
N
Chimpanzee
Pan troglodytes
XP_001165971
1581
179231
Y728
L
Y
K
D
L
D
S
Y
P
D
L
G
I
E
N
Rhesus Macaque
Macaca mulatta
XP_001082492
1581
179168
Y728
L
Y
K
D
L
D
S
Y
P
D
L
G
I
E
N
Dog
Lupus familis
XP_548020
1622
184532
C768
L
Y
E
D
L
D
R
C
P
S
L
G
I
E
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8K440
1620
183021
C767
L
C
Q
S
L
D
S
C
P
G
L
G
I
E
N
Rat
Rattus norvegicus
Q8CF82
1642
185792
H766
L
F
S
A
L
D
I
H
S
N
L
G
V
I
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509469
1722
195635
H846
L
F
S
D
L
D
I
H
S
N
L
G
V
I
S
Chicken
Gallus gallus
XP_415691
1546
175373
C710
L
F
R
G
L
D
N
C
S
D
L
G
I
I
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001092716
1654
185619
R769
L
F
A
E
L
D
C
R
P
D
L
G
I
I
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34358
1704
191394
A830
E
F
V
P
L
F
Q
A
L
E
A
I
Q
D
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84M24
1882
209045
M835
F
R
E
I
E
S
C
M
K
N
S
V
D
R
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
96.7
77.1
N.A.
73.5
40.3
N.A.
39.4
46.1
N.A.
42.4
N.A.
N.A.
N.A.
22
N.A.
Protein Similarity:
100
99.5
97.9
85.4
N.A.
83.5
60.1
N.A.
59
63.5
N.A.
60.8
N.A.
N.A.
N.A.
41.2
N.A.
P-Site Identity:
100
100
100
73.3
N.A.
66.6
33.3
N.A.
40
53.3
N.A.
60
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
80
N.A.
73.3
66.6
N.A.
73.3
73.3
N.A.
73.3
N.A.
N.A.
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.3
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
10
0
0
0
10
0
0
10
0
0
0
0
% A
% Cys:
0
10
0
0
0
0
19
28
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
46
0
82
0
0
0
46
0
0
10
10
0
% D
% Glu:
10
0
19
10
10
0
0
0
0
10
0
0
0
46
0
% E
% Phe:
10
46
0
0
0
10
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
10
0
0
0
0
0
10
0
82
0
0
0
% G
% His:
0
0
0
0
0
0
0
19
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
0
0
19
0
0
0
0
10
64
37
0
% I
% Lys:
0
0
28
0
0
0
0
0
10
0
0
0
0
0
0
% K
% Leu:
82
0
0
0
91
0
0
0
10
0
82
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
0
0
28
0
0
0
0
64
% N
% Pro:
0
0
0
10
0
0
0
0
55
0
0
0
0
0
0
% P
% Gln:
0
0
10
0
0
0
10
0
0
0
0
0
10
0
0
% Q
% Arg:
0
10
10
0
0
0
10
10
0
0
0
0
0
10
10
% R
% Ser:
0
0
19
10
0
10
37
0
28
10
10
0
0
0
28
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
10
0
0
0
0
0
0
0
0
10
19
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
37
0
0
0
0
0
28
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _