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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PCF11 All Species: 11.52
Human Site: T425 Identified Species: 31.67
UniProt: O94913 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O94913 NP_056969.2 1555 173050 T425 D V K E K R K T A E K K D K D
Chimpanzee Pan troglodytes XP_508673 1608 179455 T478 D V K E K R K T A E K K D K D
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_533992 1821 203116 A561 D V K E K R K A A E K K D K D
Cat Felis silvestris
Mouse Mus musculus
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513906 1555 171241 S455 E P K E K R K S I E K K D K E
Chicken Gallus gallus XP_417214 1503 165047 T415 V K E K R R N T E K K E K D E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001007308 1457 165663 E418 V N K H E K L E T F L K Q E I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392839 1892 210543 S437 P R L S S N S S G N L N S N S
Nematode Worm Caenorhab. elegans Q09345 823 91124
Sea Urchin Strong. purpuratus XP_787458 2645 291863 N1056 R M R K F A S N P D V D E G G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.4 N.A. 83 N.A. N.A. N.A. N.A. 75.6 68 N.A. 44.8 N.A. N.A. 24.4 20.5 23.2
Protein Similarity: 100 94.5 N.A. 83.9 N.A. N.A. N.A. N.A. 83.4 77.2 N.A. 57.6 N.A. N.A. 38.7 32.5 34.3
P-Site Identity: 100 100 N.A. 93.3 N.A. N.A. N.A. N.A. 66.6 20 N.A. 13.3 N.A. N.A. 0 0 0
P-Site Similarity: 100 100 N.A. 93.3 N.A. N.A. N.A. N.A. 86.6 60 N.A. 33.3 N.A. N.A. 6.6 0 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 12 0 12 34 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 34 0 0 0 0 0 0 0 0 12 0 12 45 12 34 % D
% Glu: 12 0 12 45 12 0 0 12 12 45 0 12 12 12 23 % E
% Phe: 0 0 0 0 12 0 0 0 0 12 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 12 0 0 0 0 12 12 % G
% His: 0 0 0 12 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 12 0 0 0 0 0 12 % I
% Lys: 0 12 56 23 45 12 45 0 0 12 56 56 12 45 0 % K
% Leu: 0 0 12 0 0 0 12 0 0 0 23 0 0 0 0 % L
% Met: 0 12 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 12 0 0 0 12 12 12 0 12 0 12 0 12 0 % N
% Pro: 12 12 0 0 0 0 0 0 12 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 12 0 0 % Q
% Arg: 12 12 12 0 12 56 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 12 12 0 23 23 0 0 0 0 12 0 12 % S
% Thr: 0 0 0 0 0 0 0 34 12 0 0 0 0 0 0 % T
% Val: 23 34 0 0 0 0 0 0 0 0 12 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _