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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FRYL All Species: 13.64
Human Site: S396 Identified Species: 50
UniProt: O94915 Number Species: 6
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O94915 NP_055845.1 3013 339598 S396 L F P K G S R S V V P R D T P
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_532369 3103 348796 S485 L F P K G S R S V V P R D T P
Cat Felis silvestris
Mouse Mus musculus
Rat Rattus norvegicus XP_002725006 3012 337963 S396 L F P K G S R S V V P R D T P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509448 3011 338588 G444 L F P K G S R G V V P R D M P
Chicken Gallus gallus
Frog Xenopus laevis NP_001104227 3010 338907 G444 L F P K G P R G V V P R D M P
Zebra Danio Brachydanio rerio NP_001153139 3142 351676 S452 L F P K G S R S V V P R D T P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VT28 3479 384333 G669 L F P K G S K G V V P R D T P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 94.2 N.A. N.A. 93.9 N.A. 62 N.A. 62 77.7 N.A. 34.4 N.A. N.A. N.A.
Protein Similarity: 100 N.A. N.A. 95.9 N.A. N.A. 96.6 N.A. 76.7 N.A. 77.4 86.1 N.A. 51.5 N.A. N.A. N.A.
P-Site Identity: 100 N.A. N.A. 100 N.A. N.A. 100 N.A. 86.6 N.A. 80 100 N.A. 86.6 N.A. N.A. N.A.
P-Site Similarity: 100 N.A. N.A. 100 N.A. N.A. 100 N.A. 86.6 N.A. 80 100 N.A. 93.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 100 0 0 43 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 100 0 0 15 0 0 0 0 0 0 0 0 % K
% Leu: 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 29 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 100 0 0 15 0 0 0 0 100 0 0 0 100 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 86 0 0 0 0 100 0 0 0 % R
% Ser: 0 0 0 0 0 86 0 58 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 72 0 % T
% Val: 0 0 0 0 0 0 0 0 100 100 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _