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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CDK14 All Species: 35.45
Human Site: Y418 Identified Species: 60
UniProt: O94921 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O94921 NP_036527.1 469 53057 Y418 Q A A L S H E Y F S D L P P R
Chimpanzee Pan troglodytes XP_519189 469 53035 Y418 Q A A L S H E Y F S D L P P R
Rhesus Macaque Macaca mulatta XP_001102520 469 53072 Y418 Q A A L S H E Y F S D L P P R
Dog Lupus familis XP_532455 469 53036 Y418 Q A A L S H E Y F S D L P P R
Cat Felis silvestris
Mouse Mus musculus O35495 469 52977 Y418 Q A A L S H E Y F S D L P P R
Rat Rattus norvegicus O35831 523 59414 Y472 E E A M K H V Y F R S L G P R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516045 337 37621 Y287 N E V V T L W Y R P P D V L L
Chicken Gallus gallus XP_418647 773 84016 Y722 Q A A L S H E Y F S D L P P R
Frog Xenopus laevis Q6DJM7 435 49211 Y384 Q A A L N H D Y F S D L P P R
Zebra Danio Brachydanio rerio Q1RLU9 418 47889 Y368 Q D A L L H P Y F N T L P P P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_523904 522 59750 T464 Y D I I E G E T I A N G F L Q
Honey Bee Apis mellifera XP_624994 494 56118 D438 S L L Q L N P D Q R I G A E E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P24100 294 34012 W244 Y K S A F P K W K P T D L E T
Baker's Yeast Sacchar. cerevisiae P17157 305 34888 R255 Q R P P R D L R Q V L Q P H T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 99.7 99.1 N.A. 98.5 43 N.A. 60.7 58.5 85.2 51.5 N.A. 48.4 50 N.A. N.A.
Protein Similarity: 100 99.5 99.7 100 N.A. 99.3 59 N.A. 63.3 59.5 89.3 63.1 N.A. 61.2 63.3 N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 46.6 N.A. 6.6 100 86.6 60 N.A. 6.6 0 N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 60 N.A. 20 100 100 66.6 N.A. 33.3 6.6 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 30.7 28.5 N.A.
Protein Similarity: N.A. N.A. N.A. 42.8 43.9 N.A.
P-Site Identity: N.A. N.A. N.A. 0 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 50 65 8 0 0 0 0 0 8 0 0 8 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 15 0 0 0 8 8 8 0 0 50 15 0 0 0 % D
% Glu: 8 15 0 0 8 0 50 0 0 0 0 0 0 15 8 % E
% Phe: 0 0 0 0 8 0 0 0 65 0 0 0 8 0 0 % F
% Gly: 0 0 0 0 0 8 0 0 0 0 0 15 8 0 0 % G
% His: 0 0 0 0 0 65 0 0 0 0 0 0 0 8 0 % H
% Ile: 0 0 8 8 0 0 0 0 8 0 8 0 0 0 0 % I
% Lys: 0 8 0 0 8 0 8 0 8 0 0 0 0 0 0 % K
% Leu: 0 8 8 58 15 8 8 0 0 0 8 65 8 15 8 % L
% Met: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 0 0 8 8 0 0 0 8 8 0 0 0 0 % N
% Pro: 0 0 8 8 0 8 15 0 0 15 8 0 65 65 8 % P
% Gln: 65 0 0 8 0 0 0 0 15 0 0 8 0 0 8 % Q
% Arg: 0 8 0 0 8 0 0 8 8 15 0 0 0 0 58 % R
% Ser: 8 0 8 0 43 0 0 0 0 50 8 0 0 0 0 % S
% Thr: 0 0 0 0 8 0 0 8 0 0 15 0 0 0 15 % T
% Val: 0 0 8 8 0 0 8 0 0 8 0 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 8 8 0 0 0 0 0 0 0 % W
% Tyr: 15 0 0 0 0 0 0 72 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _