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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GLCE All Species: 35.45
Human Site: Y458 Identified Species: 65
UniProt: O94923 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O94923 NP_056369.1 617 70101 Y458 I S T L V R A Y L L T K D H I
Chimpanzee Pan troglodytes XP_510506 617 70097 Y458 I S T L V R A Y L L T K D H I
Rhesus Macaque Macaca mulatta XP_001085491 618 70233 Y459 I S T L V R A Y L L T K D H I
Dog Lupus familis XP_852992 616 69972 Y457 I S T L V R A Y L L T K D H L
Cat Felis silvestris
Mouse Mus musculus Q9EPS3 618 70080 Y459 I S T L V R A Y L L T K D Y V
Rat Rattus norvegicus XP_343405 618 70100 Y459 I S T L V R A Y L L T K D Y V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508480 616 69238 Y457 M S T L V R A Y L L T K D R A
Chicken Gallus gallus
Frog Xenopus laevis NP_001085160 607 68310 Y448 I S T L V R A Y L L T K E Q Y
Zebra Danio Brachydanio rerio NP_998014 585 66035 D431 R A Y L M T K D D R Y L K A A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001163062 612 69086 Y452 I S V L A R A Y W H S G G D E
Honey Bee Apis mellifera XP_393602 542 62345 E388 R A Y Y H S G E E K Y L Q A A
Nematode Worm Caenorhab. elegans P46555 616 70037 F449 I S V L T R A F K H F N D E K
Sea Urchin Strong. purpuratus XP_781048 661 76192 Y502 M S V L T R A Y I K S R R K K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 99.1 97.4 N.A. 95.6 95.9 N.A. 82.3 N.A. 75 73.7 N.A. 43.1 45.2 38 44.1
Protein Similarity: 100 100 99.3 98.6 N.A. 98 98.3 N.A. 91.7 N.A. 87.8 84.2 N.A. 58.3 61.9 55.2 62.1
P-Site Identity: 100 100 100 93.3 N.A. 86.6 86.6 N.A. 80 N.A. 80 6.6 N.A. 40 0 40 33.3
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 86.6 N.A. 86.6 20 N.A. 46.6 6.6 46.6 60
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 16 0 0 8 0 85 0 0 0 0 0 0 16 24 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 8 8 0 0 0 62 8 0 % D
% Glu: 0 0 0 0 0 0 0 8 8 0 0 0 8 8 8 % E
% Phe: 0 0 0 0 0 0 0 8 0 0 8 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 8 0 0 0 0 8 8 0 0 % G
% His: 0 0 0 0 8 0 0 0 0 16 0 0 0 31 0 % H
% Ile: 70 0 0 0 0 0 0 0 8 0 0 0 0 0 24 % I
% Lys: 0 0 0 0 0 0 8 0 8 16 0 62 8 8 16 % K
% Leu: 0 0 0 93 0 0 0 0 62 62 0 16 0 0 8 % L
% Met: 16 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 8 8 0 % Q
% Arg: 16 0 0 0 0 85 0 0 0 8 0 8 8 8 0 % R
% Ser: 0 85 0 0 0 8 0 0 0 0 16 0 0 0 0 % S
% Thr: 0 0 62 0 16 8 0 0 0 0 62 0 0 0 0 % T
% Val: 0 0 24 0 62 0 0 0 0 0 0 0 0 0 16 % V
% Trp: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % W
% Tyr: 0 0 16 8 0 0 0 77 0 0 16 0 0 16 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _