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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GLS All Species: 18.18
Human Site: S165 Identified Species: 40
UniProt: O94925 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O94925 NP_055720.3 669 73461 S165 K F I T A L K S T G L R T S D
Chimpanzee Pan troglodytes XP_001167140 660 72123 S164 K F I T A L K S T G L R T S D
Rhesus Macaque Macaca mulatta XP_001115245 602 66544 I141 R K C V S S N I V L L T Q A F
Dog Lupus familis XP_545570 679 74042 S175 K F I T A L K S T G L R T S D
Cat Felis silvestris
Mouse Mus musculus Q571F8 602 66347 I141 Q K C V S S N I V L L T Q A F
Rat Rattus norvegicus P13264 674 74005 S170 K F I T A L K S T G L R T S D
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001026419 668 73493 S142 K F I T A L K S T G L R T S D
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001038509 591 65834 F138 I V L L T Q A F R K K F V I P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_725212 706 78510 D144 T T G I R R N D P R V R E L M
Honey Bee Apis mellifera XP_392523 614 69191 I153 A F R H Q F I I P D W S G F T
Nematode Worm Caenorhab. elegans Q19013 605 68317 L142 I D I V S R A L Q T D M V I P
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90.1 64.2 92.6 N.A. 64.1 94 N.A. N.A. 81 N.A. 71.5 N.A. 44.7 45.4 41.2 N.A.
Protein Similarity: 100 93.1 75.7 93.3 N.A. 75.6 95.2 N.A. N.A. 84.5 N.A. 79.8 N.A. 62 63.2 58.5 N.A.
P-Site Identity: 100 100 6.6 100 N.A. 6.6 100 N.A. N.A. 100 N.A. 0 N.A. 6.6 6.6 6.6 N.A.
P-Site Similarity: 100 100 26.6 100 N.A. 26.6 100 N.A. N.A. 100 N.A. 6.6 N.A. 13.3 6.6 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 46 0 19 0 0 0 0 0 0 19 0 % A
% Cys: 0 0 19 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 0 0 0 0 0 10 0 10 10 0 0 0 46 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % E
% Phe: 0 55 0 0 0 10 0 10 0 0 0 10 0 10 19 % F
% Gly: 0 0 10 0 0 0 0 0 0 46 0 0 10 0 0 % G
% His: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 19 0 55 10 0 0 10 28 0 0 0 0 0 19 0 % I
% Lys: 46 19 0 0 0 0 46 0 0 10 10 0 0 0 0 % K
% Leu: 0 0 10 10 0 46 0 10 0 19 64 0 0 10 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 10 % M
% Asn: 0 0 0 0 0 0 28 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 19 0 0 0 0 0 19 % P
% Gln: 10 0 0 0 10 10 0 0 10 0 0 0 19 0 0 % Q
% Arg: 10 0 10 0 10 19 0 0 10 10 0 55 0 0 0 % R
% Ser: 0 0 0 0 28 19 0 46 0 0 0 10 0 46 0 % S
% Thr: 10 10 0 46 10 0 0 0 46 10 0 19 46 0 10 % T
% Val: 0 10 0 28 0 0 0 0 19 0 10 0 19 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _