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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GLS All Species: 0.91
Human Site: T24 Identified Species: 2
UniProt: O94925 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O94925 NP_055720.3 669 73461 T24 S P A G V S A T L R R A Q P L
Chimpanzee Pan troglodytes XP_001167140 660 72123 R25 A G V S A T L R R A Q P L V T
Rhesus Macaque Macaca mulatta XP_001115245 602 66544 S24 H C R R G D W S H L S R S P L
Dog Lupus familis XP_545570 679 74042 A24 P P A A A C A A L R R P Q P L
Cat Felis silvestris
Mouse Mus musculus Q571F8 602 66347 G24 H G R R G G W G H P S R G P L
Rat Rattus norvegicus P13264 674 74005 V24 P P A A V G G V L R R T Q P L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001026419 668 73493 G24 G P P G A A G G G G P G S G S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001038509 591 65834 N24 N V R R V W R N N T D E T T V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_725212 706 78510 V24 T T Q A Q V L V H Q R A K A S
Honey Bee Apis mellifera XP_392523 614 69191 A24 T S N K R R A A V P A S K K L
Nematode Worm Caenorhab. elegans Q19013 605 68317 M27 T L E S L H E M I G S R M S K
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90.1 64.2 92.6 N.A. 64.1 94 N.A. N.A. 81 N.A. 71.5 N.A. 44.7 45.4 41.2 N.A.
Protein Similarity: 100 93.1 75.7 93.3 N.A. 75.6 95.2 N.A. N.A. 84.5 N.A. 79.8 N.A. 62 63.2 58.5 N.A.
P-Site Identity: 100 0 13.3 60 N.A. 13.3 60 N.A. N.A. 13.3 N.A. 6.6 N.A. 13.3 13.3 0 N.A.
P-Site Similarity: 100 20 20 60 N.A. 13.3 60 N.A. N.A. 20 N.A. 20 N.A. 33.3 40 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 28 28 28 10 28 19 0 10 10 19 0 10 0 % A
% Cys: 0 10 0 0 0 10 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 10 0 0 0 0 10 0 0 0 0 % D
% Glu: 0 0 10 0 0 0 10 0 0 0 0 10 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 19 0 19 19 19 19 19 10 19 0 10 10 10 0 % G
% His: 19 0 0 0 0 10 0 0 28 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % I
% Lys: 0 0 0 10 0 0 0 0 0 0 0 0 19 10 10 % K
% Leu: 0 10 0 0 10 0 19 0 28 10 0 0 10 0 55 % L
% Met: 0 0 0 0 0 0 0 10 0 0 0 0 10 0 0 % M
% Asn: 10 0 10 0 0 0 0 10 10 0 0 0 0 0 0 % N
% Pro: 19 37 10 0 0 0 0 0 0 19 10 19 0 46 0 % P
% Gln: 0 0 10 0 10 0 0 0 0 10 10 0 28 0 0 % Q
% Arg: 0 0 28 28 10 10 10 10 10 28 37 28 0 0 0 % R
% Ser: 10 10 0 19 0 10 0 10 0 0 28 10 19 10 19 % S
% Thr: 28 10 0 0 0 10 0 10 0 10 0 10 10 10 10 % T
% Val: 0 10 10 0 28 10 0 19 10 0 0 0 0 10 10 % V
% Trp: 0 0 0 0 0 10 19 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _