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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBXO21
All Species:
9.09
Human Site:
Y470
Identified Species:
22.22
UniProt:
O94952
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O94952
NP_055817.1
628
72270
Y470
G
Q
H
G
A
V
G
Y
L
V
Q
H
T
L
E
Chimpanzee
Pan troglodytes
XP_001155469
573
65480
P420
D
L
Y
L
A
M
Y
P
D
Q
V
Q
L
L
L
Rhesus Macaque
Macaca mulatta
XP_001082993
628
72292
Y470
G
Q
H
G
A
V
G
Y
L
V
Q
H
T
L
E
Dog
Lupus familis
XP_543416
644
73868
Q490
G
A
V
G
Y
L
V
Q
H
T
L
E
H
I
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8VDH1
627
72154
Y470
G
Q
H
G
A
V
G
Y
L
V
Q
H
T
L
E
Rat
Rattus norvegicus
NP_001101808
632
72700
Q478
G
A
V
G
Y
L
V
Q
H
T
L
E
H
I
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505558
303
34863
L150
D
Y
Y
N
A
L
N
L
F
I
H
Q
V
L
I
Chicken
Gallus gallus
XP_425297
610
70547
Q445
G
A
V
G
Y
L
V
Q
H
T
L
E
H
I
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_696130
637
73641
Q466
G
A
V
G
Y
L
V
Q
H
T
L
E
H
I
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396942
540
63066
A387
E
L
M
S
R
G
Q
A
N
M
I
S
Q
T
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.7
99.6
95.1
N.A.
95.8
94.3
N.A.
36.4
76.2
N.A.
56.6
N.A.
N.A.
27.2
N.A.
N.A.
Protein Similarity:
100
90.7
99.8
95.6
N.A.
97.4
95.7
N.A.
42.6
83.5
N.A.
71.4
N.A.
N.A.
45.3
N.A.
N.A.
P-Site Identity:
100
13.3
100
20
N.A.
100
20
N.A.
13.3
20
N.A.
13.3
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
100
26.6
100
33.3
N.A.
100
33.3
N.A.
33.3
33.3
N.A.
33.3
N.A.
N.A.
6.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
40
0
0
50
0
0
10
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
20
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% D
% Glu:
10
0
0
0
0
0
0
0
0
0
0
40
0
0
60
% E
% Phe:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
10
% F
% Gly:
70
0
0
70
0
10
30
0
0
0
0
0
0
0
0
% G
% His:
0
0
30
0
0
0
0
0
40
0
10
30
40
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
10
10
0
0
40
10
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
20
0
10
0
50
0
10
30
0
40
0
10
50
10
% L
% Met:
0
0
10
0
0
10
0
0
0
10
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
10
0
10
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% P
% Gln:
0
30
0
0
0
0
10
40
0
10
30
20
10
0
10
% Q
% Arg:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
10
0
0
0
0
0
0
0
10
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
40
0
0
30
10
0
% T
% Val:
0
0
40
0
0
30
40
0
0
30
10
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
20
0
40
0
10
30
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _