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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBXO21
All Species:
25.76
Human Site:
Y594
Identified Species:
62.96
UniProt:
O94952
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O94952
NP_055817.1
628
72270
Y594
S
E
F
T
G
T
H
Y
I
P
N
A
E
L
E
Chimpanzee
Pan troglodytes
XP_001155469
573
65480
H540
W
I
R
N
M
N
V
H
S
L
P
H
G
H
H
Rhesus Macaque
Macaca mulatta
XP_001082993
628
72292
Y594
S
E
F
T
G
T
H
Y
I
P
N
A
E
L
E
Dog
Lupus familis
XP_543416
644
73868
Y611
S
E
F
T
G
T
H
Y
I
P
N
A
E
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8VDH1
627
72154
Y594
S
E
F
T
G
T
H
Y
I
P
N
A
E
L
E
Rat
Rattus norvegicus
NP_001101808
632
72700
Y599
S
E
F
T
G
T
H
Y
I
P
N
A
E
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505558
303
34863
R270
D
Q
S
Y
Q
L
L
R
D
S
L
D
L
Y
L
Chicken
Gallus gallus
XP_425297
610
70547
Y566
S
E
F
T
G
T
H
Y
L
A
N
T
E
L
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_696130
637
73641
Y587
N
E
Y
S
E
T
H
Y
I
S
N
E
E
L
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396942
540
63066
I507
K
F
S
G
A
H
Y
I
P
N
E
E
K
A
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.7
99.6
95.1
N.A.
95.8
94.3
N.A.
36.4
76.2
N.A.
56.6
N.A.
N.A.
27.2
N.A.
N.A.
Protein Similarity:
100
90.7
99.8
95.6
N.A.
97.4
95.7
N.A.
42.6
83.5
N.A.
71.4
N.A.
N.A.
45.3
N.A.
N.A.
P-Site Identity:
100
0
100
100
N.A.
100
100
N.A.
0
80
N.A.
53.3
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
100
6.6
100
100
N.A.
100
100
N.A.
6.6
86.6
N.A.
80
N.A.
N.A.
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
0
0
0
10
0
50
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
0
0
10
0
0
10
0
0
0
% D
% Glu:
0
70
0
0
10
0
0
0
0
0
10
20
70
0
60
% E
% Phe:
0
10
60
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
10
60
0
0
0
0
0
0
0
10
0
0
% G
% His:
0
0
0
0
0
10
70
10
0
0
0
10
0
10
10
% H
% Ile:
0
10
0
0
0
0
0
10
60
0
0
0
0
0
0
% I
% Lys:
10
0
0
0
0
0
0
0
0
0
0
0
10
0
10
% K
% Leu:
0
0
0
0
0
10
10
0
10
10
10
0
10
70
10
% L
% Met:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
10
0
10
0
0
0
10
70
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
10
50
10
0
0
0
0
% P
% Gln:
0
10
0
0
10
0
0
0
0
0
0
0
0
0
10
% Q
% Arg:
0
0
10
0
0
0
0
10
0
0
0
0
0
0
0
% R
% Ser:
60
0
20
10
0
0
0
0
10
20
0
0
0
0
0
% S
% Thr:
0
0
0
60
0
70
0
0
0
0
0
10
0
0
0
% T
% Val:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% V
% Trp:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
10
0
0
10
70
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _