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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FBXO21 All Species: 25.76
Human Site: Y594 Identified Species: 62.96
UniProt: O94952 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O94952 NP_055817.1 628 72270 Y594 S E F T G T H Y I P N A E L E
Chimpanzee Pan troglodytes XP_001155469 573 65480 H540 W I R N M N V H S L P H G H H
Rhesus Macaque Macaca mulatta XP_001082993 628 72292 Y594 S E F T G T H Y I P N A E L E
Dog Lupus familis XP_543416 644 73868 Y611 S E F T G T H Y I P N A E L E
Cat Felis silvestris
Mouse Mus musculus Q8VDH1 627 72154 Y594 S E F T G T H Y I P N A E L E
Rat Rattus norvegicus NP_001101808 632 72700 Y599 S E F T G T H Y I P N A E L E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505558 303 34863 R270 D Q S Y Q L L R D S L D L Y L
Chicken Gallus gallus XP_425297 610 70547 Y566 S E F T G T H Y L A N T E L E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_696130 637 73641 Y587 N E Y S E T H Y I S N E E L Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396942 540 63066 I507 K F S G A H Y I P N E E K A K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90.7 99.6 95.1 N.A. 95.8 94.3 N.A. 36.4 76.2 N.A. 56.6 N.A. N.A. 27.2 N.A. N.A.
Protein Similarity: 100 90.7 99.8 95.6 N.A. 97.4 95.7 N.A. 42.6 83.5 N.A. 71.4 N.A. N.A. 45.3 N.A. N.A.
P-Site Identity: 100 0 100 100 N.A. 100 100 N.A. 0 80 N.A. 53.3 N.A. N.A. 0 N.A. N.A.
P-Site Similarity: 100 6.6 100 100 N.A. 100 100 N.A. 6.6 86.6 N.A. 80 N.A. N.A. 20 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 10 0 0 0 0 10 0 50 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 0 0 0 0 0 10 0 0 10 0 0 0 % D
% Glu: 0 70 0 0 10 0 0 0 0 0 10 20 70 0 60 % E
% Phe: 0 10 60 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 10 60 0 0 0 0 0 0 0 10 0 0 % G
% His: 0 0 0 0 0 10 70 10 0 0 0 10 0 10 10 % H
% Ile: 0 10 0 0 0 0 0 10 60 0 0 0 0 0 0 % I
% Lys: 10 0 0 0 0 0 0 0 0 0 0 0 10 0 10 % K
% Leu: 0 0 0 0 0 10 10 0 10 10 10 0 10 70 10 % L
% Met: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 0 0 10 0 10 0 0 0 10 70 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 10 50 10 0 0 0 0 % P
% Gln: 0 10 0 0 10 0 0 0 0 0 0 0 0 0 10 % Q
% Arg: 0 0 10 0 0 0 0 10 0 0 0 0 0 0 0 % R
% Ser: 60 0 20 10 0 0 0 0 10 20 0 0 0 0 0 % S
% Thr: 0 0 0 60 0 70 0 0 0 0 0 10 0 0 0 % T
% Val: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % V
% Trp: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 10 10 0 0 10 70 0 0 0 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _