Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KDM4B All Species: 16.97
Human Site: Y948 Identified Species: 41.48
UniProt: O94953 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O94953 NP_055830.1 1096 121897 Y948 G A A S Q T C Y E V N F D D G
Chimpanzee Pan troglodytes XP_001140503 1096 121857 Y948 G A A S Q T C Y E V N F D D G
Rhesus Macaque Macaca mulatta XP_001083379 1096 121796 Y948 G A A T Q T C Y E V N F D D G
Dog Lupus familis XP_533946 1202 133877 Y1054 G T S A Q T F Y E V N F D D G
Cat Felis silvestris
Mouse Mus musculus Q91VY5 1086 121585 Y936 G T T A Q T F Y E V N F D D G
Rat Rattus norvegicus A1A5Q5 510 57169 T367 V I Q A P R K T W G L K H L R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507384 1068 120585 V924 R F Y Q C E V V R L T T E T F
Chicken Gallus gallus XP_422410 1058 119418 V914 R F Y Q C E V V S L A K E T F
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001076274 1134 127451 H988 N A S Y I K E H V H R Y Y Q V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V6L0 590 66418 I447 K Q E L L E Y I D D G T E D D
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 97.4 80.8 N.A. 79.6 31.9 N.A. 51.1 50.6 N.A. 55.8 N.A. 30.5 N.A. N.A. N.A.
Protein Similarity: 100 99.5 98.2 83.5 N.A. 86.5 39.3 N.A. 65.6 66.7 N.A. 67.8 N.A. 39.9 N.A. N.A. N.A.
P-Site Identity: 100 100 93.3 73.3 N.A. 73.3 0 N.A. 0 0 N.A. 6.6 N.A. 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 86.6 N.A. 80 6.6 N.A. 13.3 13.3 N.A. 26.6 N.A. 20 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 40 30 30 0 0 0 0 0 0 10 0 0 0 0 % A
% Cys: 0 0 0 0 20 0 30 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 10 10 0 0 50 60 10 % D
% Glu: 0 0 10 0 0 30 10 0 50 0 0 0 30 0 0 % E
% Phe: 0 20 0 0 0 0 20 0 0 0 0 50 0 0 20 % F
% Gly: 50 0 0 0 0 0 0 0 0 10 10 0 0 0 50 % G
% His: 0 0 0 0 0 0 0 10 0 10 0 0 10 0 0 % H
% Ile: 0 10 0 0 10 0 0 10 0 0 0 0 0 0 0 % I
% Lys: 10 0 0 0 0 10 10 0 0 0 0 20 0 0 0 % K
% Leu: 0 0 0 10 10 0 0 0 0 20 10 0 0 10 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 0 0 0 0 0 0 0 0 0 50 0 0 0 0 % N
% Pro: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 10 10 20 50 0 0 0 0 0 0 0 0 10 0 % Q
% Arg: 20 0 0 0 0 10 0 0 10 0 10 0 0 0 10 % R
% Ser: 0 0 20 20 0 0 0 0 10 0 0 0 0 0 0 % S
% Thr: 0 20 10 10 0 50 0 10 0 0 10 20 0 20 0 % T
% Val: 10 0 0 0 0 0 20 20 10 50 0 0 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % W
% Tyr: 0 0 20 10 0 0 10 50 0 0 0 10 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _