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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLCO2B1
All Species:
20
Human Site:
S159
Identified Species:
55
UniProt:
O94956
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O94956
NP_001138683.1
709
76699
S159
M
P
Q
D
F
K
A
S
L
C
L
P
T
T
S
Chimpanzee
Pan troglodytes
XP_001174975
709
76770
S159
M
P
Q
D
F
K
A
S
L
C
L
P
T
T
S
Rhesus Macaque
Macaca mulatta
XP_001085104
709
76937
S159
M
P
Q
D
F
K
A
S
L
C
L
P
T
T
S
Dog
Lupus familis
XP_542310
711
76672
S159
M
P
Q
D
Y
E
A
S
L
C
Q
P
T
T
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BXB6
683
74513
S151
R
S
L
D
F
E
A
S
L
C
L
P
T
T
M
Rat
Rattus norvegicus
Q9JHI3
682
74196
S150
R
S
Q
D
F
E
A
S
L
C
L
P
T
T
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417242
643
70360
D148
E
Y
D
H
N
T
T
D
L
C
Q
P
E
G
L
Frog
Xenopus laevis
NP_001089875
560
60901
F66
I
S
T
I
E
K
R
F
G
I
S
S
Q
T
S
Zebra Danio
Brachydanio rerio
NP_001032767
677
74880
Q148
E
S
S
P
T
C
S
Q
N
D
T
D
P
Q
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
96.9
79.4
N.A.
71.2
72.6
N.A.
N.A.
46.9
40.7
45.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.4
97.4
87.7
N.A.
80.9
81.5
N.A.
N.A.
65.4
55.4
63.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
73.3
N.A.
66.6
73.3
N.A.
N.A.
20
20
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
86.6
N.A.
73.3
80
N.A.
N.A.
20
26.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
67
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
12
0
0
0
78
0
0
0
0
0
% C
% Asp:
0
0
12
67
0
0
0
12
0
12
0
12
0
0
0
% D
% Glu:
23
0
0
0
12
34
0
0
0
0
0
0
12
0
0
% E
% Phe:
0
0
0
0
56
0
0
12
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
12
0
0
0
0
12
0
% G
% His:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
12
0
0
12
0
0
0
0
0
12
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
45
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
12
0
0
0
0
0
78
0
56
0
0
0
34
% L
% Met:
45
0
0
0
0
0
0
0
0
0
0
0
0
0
23
% M
% Asn:
0
0
0
0
12
0
0
0
12
0
0
0
0
0
0
% N
% Pro:
0
45
0
12
0
0
0
0
0
0
0
78
12
0
0
% P
% Gln:
0
0
56
0
0
0
0
12
0
0
23
0
12
12
0
% Q
% Arg:
23
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% R
% Ser:
0
45
12
0
0
0
12
67
0
0
12
12
0
0
45
% S
% Thr:
0
0
12
0
12
12
12
0
0
0
12
0
67
78
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
12
0
0
12
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _