KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP19
All Species:
13.03
Human Site:
S461
Identified Species:
47.78
UniProt:
O94966
Number Species:
6
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O94966
NP_006668.1
1318
145651
S461
K
P
E
T
H
L
A
S
P
K
P
T
C
M
V
Chimpanzee
Pan troglodytes
XP_516454
1415
156345
S558
K
P
E
T
H
L
A
S
P
K
P
T
C
M
V
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_862305
1074
119871
R284
L
R
D
F
F
H
D
R
S
F
E
T
E
I
N
Cat
Felis silvestris
Mouse
Mus musculus
Q3UJD6
1360
150530
S503
K
P
D
P
H
L
A
S
P
K
P
T
C
M
V
Rat
Rattus norvegicus
Q6J1Y9
1357
150284
S500
K
P
E
P
H
L
A
S
P
K
P
T
C
M
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O22207
924
103856
G134
N
Q
L
R
S
W
Y
G
G
G
P
T
L
A
R
Baker's Yeast
Sacchar. cerevisiae
P39538
1254
143174
F438
I
M
Q
R
N
A
A
F
P
P
S
M
F
K
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.4
N.A.
78.5
N.A.
81
81.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
92.5
N.A.
79.7
N.A.
85.5
85.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
N.A.
6.6
N.A.
86.6
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
20
N.A.
93.3
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.1
22.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.6
39
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
15
72
0
0
0
0
0
0
15
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
58
0
0
% C
% Asp:
0
0
29
0
0
0
15
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
43
0
0
0
0
0
0
0
15
0
15
0
0
% E
% Phe:
0
0
0
15
15
0
0
15
0
15
0
0
15
0
0
% F
% Gly:
0
0
0
0
0
0
0
15
15
15
0
0
0
0
0
% G
% His:
0
0
0
0
58
15
0
0
0
0
0
0
0
0
0
% H
% Ile:
15
0
0
0
0
0
0
0
0
0
0
0
0
15
0
% I
% Lys:
58
0
0
0
0
0
0
0
0
58
0
0
0
15
0
% K
% Leu:
15
0
15
0
0
58
0
0
0
0
0
0
15
0
0
% L
% Met:
0
15
0
0
0
0
0
0
0
0
0
15
0
58
0
% M
% Asn:
15
0
0
0
15
0
0
0
0
0
0
0
0
0
15
% N
% Pro:
0
58
0
29
0
0
0
0
72
15
72
0
0
0
0
% P
% Gln:
0
15
15
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
15
0
29
0
0
0
15
0
0
0
0
0
0
15
% R
% Ser:
0
0
0
0
15
0
0
58
15
0
15
0
0
0
15
% S
% Thr:
0
0
0
29
0
0
0
0
0
0
0
86
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
58
% V
% Trp:
0
0
0
0
0
15
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
15
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _