KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AP2A2
All Species:
22.73
Human Site:
S225
Identified Species:
45.45
UniProt:
O94973
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O94973
NP_036437.1
939
103960
S225
N
P
E
E
F
K
T
S
V
S
L
A
V
S
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001116794
953
104990
R207
S
V
S
L
A
V
S
R
L
S
R
I
V
T
S
Dog
Lupus familis
XP_533200
1007
111388
S297
N
P
E
E
F
K
T
S
V
S
L
A
V
S
R
Cat
Felis silvestris
Mouse
Mus musculus
P17427
938
104082
S225
N
P
E
E
F
K
T
S
V
S
L
A
V
S
R
Rat
Rattus norvegicus
P18484
938
104026
S225
N
P
E
E
F
K
T
S
V
S
L
A
V
S
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001012914
938
104174
S225
N
P
E
E
F
K
T
S
V
S
L
A
V
S
R
Frog
Xenopus laevis
NP_001089303
939
104392
S225
N
P
E
E
F
K
T
S
V
S
L
A
V
S
R
Zebra Danio
Brachydanio rerio
XP_001922436
930
103267
C225
N
P
D
E
F
K
T
C
V
S
L
A
V
S
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91926
940
105602
C224
N
P
D
E
Y
K
G
C
V
N
L
A
V
S
R
Honey Bee
Apis mellifera
XP_394621
937
104937
C224
N
P
D
E
Y
K
G
C
V
S
L
A
V
S
R
Nematode Worm
Caenorhab. elegans
NP_509572
925
104161
A224
W
P
E
E
Y
K
G
A
V
P
L
A
I
S
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38065
1025
114993
D253
E
F
I
A
K
Y
I
D
P
S
Y
C
T
R
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
93.6
89.3
N.A.
97.2
97.2
N.A.
N.A.
95.3
87.6
84.3
N.A.
69.8
71
66.1
N.A.
Protein Similarity:
100
N.A.
94.5
91.3
N.A.
98.6
98.8
N.A.
N.A.
97.7
94.2
91.1
N.A.
81.4
82.2
78.4
N.A.
P-Site Identity:
100
N.A.
13.3
100
N.A.
100
100
N.A.
N.A.
100
100
86.6
N.A.
66.6
73.3
60
N.A.
P-Site Similarity:
100
N.A.
40
100
N.A.
100
100
N.A.
N.A.
100
100
93.3
N.A.
86.6
86.6
80
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
45.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
9
0
0
9
0
0
0
84
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
25
0
0
0
9
0
0
0
% C
% Asp:
0
0
25
0
0
0
0
9
0
0
0
0
0
0
0
% D
% Glu:
9
0
59
84
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
9
0
0
59
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
25
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
9
0
0
0
9
0
0
0
0
9
9
0
0
% I
% Lys:
0
0
0
0
9
84
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
9
0
0
0
0
9
0
84
0
0
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
75
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% N
% Pro:
0
84
0
0
0
0
0
0
9
9
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
9
0
0
9
0
0
9
84
% R
% Ser:
9
0
9
0
0
0
9
50
0
84
0
0
0
84
9
% S
% Thr:
0
0
0
0
0
0
59
0
0
0
0
0
9
9
0
% T
% Val:
0
9
0
0
0
9
0
0
84
0
0
0
84
0
0
% V
% Trp:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
25
9
0
0
0
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _