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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AP2A2
All Species:
18.48
Human Site:
S650
Identified Species:
36.97
UniProt:
O94973
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O94973
NP_036437.1
939
103960
S650
E
P
A
P
A
S
T
S
A
V
S
T
P
S
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001116794
953
104990
S626
E
P
A
P
A
S
T
S
A
M
S
T
P
S
P
Dog
Lupus familis
XP_533200
1007
111388
A722
E
P
A
P
A
S
A
A
S
T
P
S
P
S
A
Cat
Felis silvestris
Mouse
Mus musculus
P17427
938
104082
S650
E
P
V
P
A
S
T
S
A
A
S
T
P
S
P
Rat
Rattus norvegicus
P18484
938
104026
S650
E
P
V
P
A
S
T
S
A
A
S
T
P
S
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001012914
938
104174
S650
E
P
A
S
V
N
A
S
A
V
S
T
P
S
P
Frog
Xenopus laevis
NP_001089303
939
104392
T651
T
E
H
A
P
V
S
T
S
S
T
P
S
P
S
Zebra Danio
Brachydanio rerio
XP_001922436
930
103267
N651
G
G
E
R
G
G
D
N
S
T
I
S
T
P
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91926
940
105602
S651
N
N
A
L
V
N
N
S
H
S
K
L
N
N
S
Honey Bee
Apis mellifera
XP_394621
937
104937
G651
E
A
P
S
S
V
T
G
A
V
N
N
T
S
A
Nematode Worm
Caenorhab. elegans
NP_509572
925
104161
F650
G
S
T
S
L
V
D
F
D
S
T
N
D
T
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38065
1025
114993
R713
S
K
R
A
N
S
S
R
S
I
M
V
P
M
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
93.6
89.3
N.A.
97.2
97.2
N.A.
N.A.
95.3
87.6
84.3
N.A.
69.8
71
66.1
N.A.
Protein Similarity:
100
N.A.
94.5
91.3
N.A.
98.6
98.8
N.A.
N.A.
97.7
94.2
91.1
N.A.
81.4
82.2
78.4
N.A.
P-Site Identity:
100
N.A.
93.3
53.3
N.A.
86.6
86.6
N.A.
N.A.
73.3
0
0
N.A.
13.3
33.3
0
N.A.
P-Site Similarity:
100
N.A.
100
73.3
N.A.
86.6
86.6
N.A.
N.A.
80
26.6
20
N.A.
26.6
46.6
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
45.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
42
17
42
0
17
9
50
17
0
0
0
0
17
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
17
0
9
0
0
0
9
0
0
% D
% Glu:
59
9
9
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% F
% Gly:
17
9
0
0
9
9
0
9
0
0
0
0
0
0
0
% G
% His:
0
0
9
0
0
0
0
0
9
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
9
9
0
0
0
0
% I
% Lys:
0
9
0
0
0
0
0
0
0
0
9
0
0
0
0
% K
% Leu:
0
0
0
9
9
0
0
0
0
0
0
9
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
9
9
0
0
9
0
% M
% Asn:
9
9
0
0
9
17
9
9
0
0
9
17
9
9
0
% N
% Pro:
0
50
9
42
9
0
0
0
0
0
9
9
59
17
50
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
9
9
0
0
0
9
0
0
0
0
0
0
0
% R
% Ser:
9
9
0
25
9
50
17
50
34
25
42
17
9
59
25
% S
% Thr:
9
0
9
0
0
0
42
9
0
17
17
42
17
9
9
% T
% Val:
0
0
17
0
17
25
0
0
0
25
0
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _