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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AP2A2 All Species: 43.03
Human Site: T919 Identified Species: 86.06
UniProt: O94973 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O94973 NP_036437.1 939 103960 T919 Q A Q M Y R L T L R T S K E A
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001116794 953 104990 T933 Q A Q M Y R L T L R T S K E A
Dog Lupus familis XP_533200 1007 111388 T987 Q A Q M Y R L T L R T S K E T
Cat Felis silvestris
Mouse Mus musculus P17427 938 104082 T918 Q A Q M Y R L T L R T S K D T
Rat Rattus norvegicus P18484 938 104026 T918 Q A Q M Y R L T L R T S K D T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001012914 938 104174 T918 Q A Q M Y R L T L R T S K E A
Frog Xenopus laevis NP_001089303 939 104392 T919 Q A Q M Y R L T I R T S R E D
Zebra Danio Brachydanio rerio XP_001922436 930 103267 T910 Q A Q M Y R L T L R S S K D T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P91926 940 105602 T920 Q A Q M F R L T V R A S K E T
Honey Bee Apis mellifera XP_394621 937 104937 T917 Q A Q M F R L T V R S S K E S
Nematode Worm Caenorhab. elegans NP_509572 925 104161 T905 Q A K M Y R L T I R S S K D T
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P38065 1025 114993 C1003 N G T V N V T C K T T T A G P
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 93.6 89.3 N.A. 97.2 97.2 N.A. N.A. 95.3 87.6 84.3 N.A. 69.8 71 66.1 N.A.
Protein Similarity: 100 N.A. 94.5 91.3 N.A. 98.6 98.8 N.A. N.A. 97.7 94.2 91.1 N.A. 81.4 82.2 78.4 N.A.
P-Site Identity: 100 N.A. 100 93.3 N.A. 86.6 86.6 N.A. N.A. 100 80 80 N.A. 73.3 73.3 66.6 N.A.
P-Site Similarity: 100 N.A. 100 93.3 N.A. 93.3 93.3 N.A. N.A. 100 93.3 93.3 N.A. 86.6 100 93.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 45.5 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 92 0 0 0 0 0 0 0 0 9 0 9 0 25 % A
% Cys: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 34 9 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 59 0 % E
% Phe: 0 0 0 0 17 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 9 0 0 0 0 0 0 0 0 0 0 0 9 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 17 0 0 0 0 0 0 % I
% Lys: 0 0 9 0 0 0 0 0 9 0 0 0 84 0 0 % K
% Leu: 0 0 0 0 0 0 92 0 59 0 0 0 0 0 0 % L
% Met: 0 0 0 92 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 9 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % P
% Gln: 92 0 84 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 92 0 0 0 92 0 0 9 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 25 92 0 0 9 % S
% Thr: 0 0 9 0 0 0 9 92 0 9 67 9 0 0 50 % T
% Val: 0 0 0 9 0 9 0 0 17 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 75 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _