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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ARHGEF15
All Species:
13.94
Human Site:
Y507
Identified Species:
51.11
UniProt:
O94989
Number Species:
6
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O94989
NP_776089.2
841
91940
Y507
A
V
G
P
F
S
V
Y
V
D
Y
V
R
N
Q
Chimpanzee
Pan troglodytes
XP_001166994
841
91975
Y507
A
V
G
P
F
S
V
Y
V
D
Y
V
R
N
Q
Rhesus Macaque
Macaca mulatta
XP_001118167
614
69011
T293
N
Q
Q
Y
Q
E
E
T
Y
S
R
L
M
D
T
Dog
Lupus familis
XP_849991
842
91922
Y508
A
V
G
P
F
S
V
Y
V
D
Y
V
R
N
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q5FWH6
849
92927
Y515
A
V
G
P
F
F
V
Y
V
D
Y
V
R
N
Q
Rat
Rattus norvegicus
Q5BKC9
701
80989
E380
Q
E
K
T
A
F
R
E
L
I
A
Q
L
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520926
611
70617
E290
Q
E
K
A
A
F
R
E
V
I
S
Q
L
E
L
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
71.2
88.8
N.A.
84.5
29.3
N.A.
27.8
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.2
72
91
N.A.
89
45.6
N.A.
42.8
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
100
N.A.
93.3
0
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
13.3
100
N.A.
93.3
6.6
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
58
0
0
15
29
0
0
0
0
0
15
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
58
0
0
0
15
0
% D
% Glu:
0
29
0
0
0
15
15
29
0
0
0
0
0
29
0
% E
% Phe:
0
0
0
0
58
43
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
58
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
29
0
0
0
0
0
% I
% Lys:
0
0
29
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
15
0
0
15
29
0
29
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
15
0
0
% M
% Asn:
15
0
0
0
0
0
0
0
0
0
0
0
0
58
0
% N
% Pro:
0
0
0
58
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
29
15
15
0
15
0
0
0
0
0
0
29
0
0
58
% Q
% Arg:
0
0
0
0
0
0
29
0
0
0
15
0
58
0
0
% R
% Ser:
0
0
0
0
0
43
0
0
0
15
15
0
0
0
0
% S
% Thr:
0
0
0
15
0
0
0
15
0
0
0
0
0
0
15
% T
% Val:
0
58
0
0
0
0
58
0
72
0
0
58
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
15
0
0
0
58
15
0
58
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _