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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HEXIM1
All Species:
13.26
Human Site:
S355
Identified Species:
32.41
UniProt:
O94992
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O94992
NP_006451.1
359
40623
S355
Q
Q
E
R
A
P
L
S
K
F
G
D
_
_
_
Chimpanzee
Pan troglodytes
XP_001141303
308
35029
Rhesus Macaque
Macaca mulatta
XP_001115260
359
40552
S355
Q
Q
E
R
A
P
L
S
K
F
G
D
_
_
_
Dog
Lupus familis
XP_848322
303
34138
Cat
Felis silvestris
Mouse
Mus musculus
Q8R409
356
40225
S352
Q
Q
E
R
A
P
L
S
K
F
G
D
_
_
_
Rat
Rattus norvegicus
Q5M9G1
356
40299
S352
Q
Q
E
R
A
P
P
S
K
F
G
D
_
_
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512237
286
31342
Chicken
Gallus gallus
Frog
Xenopus laevis
Q4V7W3
285
32469
Zebra Danio
Brachydanio rerio
A5D8S8
319
36200
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792438
230
26777
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
37.3
98
76
N.A.
85.7
85.5
N.A.
40.1
N.A.
42.9
46.5
N.A.
N.A.
N.A.
N.A.
25.3
Protein Similarity:
100
50.7
98.3
77.9
N.A.
89.1
88.8
N.A.
49.8
N.A.
55.9
62.9
N.A.
N.A.
N.A.
N.A.
39.5
P-Site Identity:
100
0
100
0
N.A.
100
91.6
N.A.
0
N.A.
0
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
0
100
0
N.A.
100
91.6
N.A.
0
N.A.
0
0
N.A.
N.A.
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
40
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
40
0
0
0
% D
% Glu:
0
0
40
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
40
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
40
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
40
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
30
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
40
10
0
0
0
0
0
0
0
0
% P
% Gln:
40
40
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
40
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
40
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
40
40
40
% _