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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HEXIM1
All Species:
14.24
Human Site:
T206
Identified Species:
34.81
UniProt:
O94992
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O94992
NP_006451.1
359
40623
T206
P
V
A
P
Y
N
T
T
Q
F
L
M
D
D
H
Chimpanzee
Pan troglodytes
XP_001141303
308
35029
N171
N
T
T
Q
F
L
M
N
D
R
D
P
E
E
P
Rhesus Macaque
Macaca mulatta
XP_001115260
359
40552
T206
P
V
A
P
Y
N
T
T
Q
F
L
M
D
D
H
Dog
Lupus familis
XP_848322
303
34138
T166
Q
E
E
P
D
L
K
T
G
L
Y
P
K
R
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8R409
356
40225
T203
P
V
A
P
Y
N
T
T
Q
F
L
M
D
D
H
Rat
Rattus norvegicus
Q5M9G1
356
40299
T203
P
V
A
P
Y
N
T
T
Q
F
L
M
D
D
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512237
286
31342
Q149
H
R
R
R
P
S
K
Q
K
R
P
R
R
P
Y
Chicken
Gallus gallus
Frog
Xenopus laevis
Q4V7W3
285
32469
R148
P
D
L
C
P
P
P
R
K
S
S
A
A
L
P
Zebra Danio
Brachydanio rerio
A5D8S8
319
36200
G178
E
L
G
G
R
K
S
G
A
I
R
S
E
D
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792438
230
26777
D93
T
T
Q
F
L
M
E
D
H
K
V
V
T
P
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
37.3
98
76
N.A.
85.7
85.5
N.A.
40.1
N.A.
42.9
46.5
N.A.
N.A.
N.A.
N.A.
25.3
Protein Similarity:
100
50.7
98.3
77.9
N.A.
89.1
88.8
N.A.
49.8
N.A.
55.9
62.9
N.A.
N.A.
N.A.
N.A.
39.5
P-Site Identity:
100
0
100
13.3
N.A.
100
100
N.A.
0
N.A.
6.6
6.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
20
100
13.3
N.A.
100
100
N.A.
20
N.A.
13.3
26.6
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
40
0
0
0
0
0
10
0
0
10
10
0
10
% A
% Cys:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
10
0
0
10
10
0
10
0
40
50
10
% D
% Glu:
10
10
10
0
0
0
10
0
0
0
0
0
20
10
0
% E
% Phe:
0
0
0
10
10
0
0
0
0
40
0
0
0
0
0
% F
% Gly:
0
0
10
10
0
0
0
10
10
0
0
0
0
0
0
% G
% His:
10
0
0
0
0
0
0
0
10
0
0
0
0
0
40
% H
% Ile:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
10
20
0
20
10
0
0
10
0
0
% K
% Leu:
0
10
10
0
10
20
0
0
0
10
40
0
0
10
0
% L
% Met:
0
0
0
0
0
10
10
0
0
0
0
40
0
0
0
% M
% Asn:
10
0
0
0
0
40
0
10
0
0
0
0
0
0
0
% N
% Pro:
50
0
0
50
20
10
10
0
0
0
10
20
0
20
20
% P
% Gln:
10
0
10
10
0
0
0
10
40
0
0
0
0
0
0
% Q
% Arg:
0
10
10
10
10
0
0
10
0
20
10
10
10
10
0
% R
% Ser:
0
0
0
0
0
10
10
0
0
10
10
10
0
0
0
% S
% Thr:
10
20
10
0
0
0
40
50
0
0
0
0
10
0
10
% T
% Val:
0
40
0
0
0
0
0
0
0
0
10
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
40
0
0
0
0
0
10
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _