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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HEXIM1
All Species:
15.15
Human Site:
T236
Identified Species:
37.04
UniProt:
O94992
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O94992
NP_006451.1
359
40623
T236
A
A
A
K
S
D
D
T
S
D
D
D
F
M
E
Chimpanzee
Pan troglodytes
XP_001141303
308
35029
S200
G
E
S
E
A
G
D
S
D
G
R
G
R
A
H
Rhesus Macaque
Macaca mulatta
XP_001115260
359
40552
T236
A
A
A
K
S
D
D
T
S
D
D
D
F
M
E
Dog
Lupus familis
XP_848322
303
34138
G195
E
A
G
E
E
D
G
G
S
D
G
M
G
G
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8R409
356
40225
T233
A
A
A
K
S
D
D
T
S
D
E
D
F
V
E
Rat
Rattus norvegicus
Q5M9G1
356
40299
T233
A
A
A
K
S
D
D
T
S
D
E
D
F
V
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512237
286
31342
L178
Q
S
Q
R
A
S
R
L
R
A
Q
M
F
A
K
Chicken
Gallus gallus
Frog
Xenopus laevis
Q4V7W3
285
32469
D177
D
D
L
E
E
E
E
D
E
A
G
S
D
G
M
Zebra Danio
Brachydanio rerio
A5D8S8
319
36200
M209
G
G
G
G
S
D
G
M
G
R
P
G
Q
A
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792438
230
26777
L122
L
S
S
S
D
E
V
L
E
N
E
N
E
E
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
37.3
98
76
N.A.
85.7
85.5
N.A.
40.1
N.A.
42.9
46.5
N.A.
N.A.
N.A.
N.A.
25.3
Protein Similarity:
100
50.7
98.3
77.9
N.A.
89.1
88.8
N.A.
49.8
N.A.
55.9
62.9
N.A.
N.A.
N.A.
N.A.
39.5
P-Site Identity:
100
6.6
100
26.6
N.A.
86.6
86.6
N.A.
6.6
N.A.
0
13.3
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
33.3
100
40
N.A.
100
100
N.A.
33.3
N.A.
20
13.3
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
40
50
40
0
20
0
0
0
0
20
0
0
0
30
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
10
0
0
10
60
50
10
10
50
20
40
10
0
10
% D
% Glu:
10
10
0
30
20
20
10
0
20
0
30
0
10
10
40
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
50
0
0
% F
% Gly:
20
10
20
10
0
10
20
10
10
10
20
20
10
20
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
40
0
0
0
0
0
0
0
0
0
0
10
% K
% Leu:
10
0
10
0
0
0
0
20
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
10
0
0
0
20
0
20
10
% M
% Asn:
0
0
0
0
0
0
0
0
0
10
0
10
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% P
% Gln:
10
0
10
0
0
0
0
0
0
0
10
0
10
0
0
% Q
% Arg:
0
0
0
10
0
0
10
0
10
10
10
0
10
0
0
% R
% Ser:
0
20
20
10
50
10
0
10
50
0
0
10
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
40
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
10
0
0
0
0
0
0
20
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _