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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SEMA3D All Species: 33.33
Human Site: S409 Identified Species: 73.33
UniProt: O95025 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95025 NP_689967.2 777 89651 S409 T Y D P L I K S T R D F P D D
Chimpanzee Pan troglodytes XP_527805 777 89607 S409 T Y D P L I K S T R D F P D D
Rhesus Macaque Macaca mulatta XP_001107897 777 89509 S409 T Y D P L I K S T R D F P D D
Dog Lupus familis XP_533138 777 89667 S409 T Y D P L I K S T R D F P D D
Cat Felis silvestris
Mouse Mus musculus Q8BH34 777 89530 S409 T Y D P L I K S T R D F P D D
Rat Rattus norvegicus Q63548 772 88790 T392 T F G G F D S T K D L P D D V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505929 813 93371 S445 T Y D P L I K S T R D F P D D
Chicken Gallus gallus Q90663 761 87282 S397 T Y D P L I K S T R D F P D E
Frog Xenopus laevis NP_001087589 685 78447 Y359 K A S A V C V Y S M A D I R G
Zebra Danio Brachydanio rerio Q9W6G6 764 87841 T413 T Y D P H I K T T K D F P D E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24322 850 95478 A403 F T Q I A V D A Q I K T P G G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 98.8 96.1 N.A. 92.9 54.3 N.A. 85.2 84 66.1 62.6 N.A. 27.6 N.A. N.A. N.A.
Protein Similarity: 100 99.8 99.3 98.8 N.A. 96.6 73.8 N.A. 90.9 92 76.5 79 N.A. 46.2 N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 13.3 N.A. 100 93.3 0 73.3 N.A. 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 26.6 N.A. 100 100 13.3 93.3 N.A. 20 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 10 10 0 0 10 0 0 10 0 0 0 0 % A
% Cys: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 73 0 0 10 10 0 0 10 73 10 10 82 55 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 19 % E
% Phe: 10 10 0 0 10 0 0 0 0 0 0 73 0 0 0 % F
% Gly: 0 0 10 10 0 0 0 0 0 0 0 0 0 10 19 % G
% His: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 10 0 73 0 0 0 10 0 0 10 0 0 % I
% Lys: 10 0 0 0 0 0 73 0 10 10 10 0 0 0 0 % K
% Leu: 0 0 0 0 64 0 0 0 0 0 10 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 73 0 0 0 0 0 0 0 10 82 0 0 % P
% Gln: 0 0 10 0 0 0 0 0 10 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 64 0 0 0 10 0 % R
% Ser: 0 0 10 0 0 0 10 64 10 0 0 0 0 0 0 % S
% Thr: 82 10 0 0 0 0 0 19 73 0 0 10 0 0 0 % T
% Val: 0 0 0 0 10 10 10 0 0 0 0 0 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 73 0 0 0 0 0 10 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _