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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEMA3D
All Species:
30.91
Human Site:
S721
Identified Species:
68
UniProt:
O95025
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95025
NP_689967.2
777
89651
S721
K
D
Y
I
Q
I
L
S
S
P
N
F
S
L
D
Chimpanzee
Pan troglodytes
XP_527805
777
89607
S721
K
D
Y
I
Q
I
L
S
S
P
N
F
S
L
D
Rhesus Macaque
Macaca mulatta
XP_001107897
777
89509
S721
K
D
Y
I
Q
I
L
S
S
P
N
F
S
L
D
Dog
Lupus familis
XP_533138
777
89667
S721
K
D
Y
I
Q
I
L
S
S
P
N
F
S
L
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8BH34
777
89530
S721
K
D
Y
I
Q
I
L
S
S
P
N
F
S
L
D
Rat
Rattus norvegicus
Q63548
772
88790
N712
R
D
F
M
Q
L
I
N
H
P
N
L
N
T
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505929
813
93371
S757
K
D
Y
I
Q
I
L
S
S
P
N
F
S
L
D
Chicken
Gallus gallus
Q90663
761
87282
S709
K
D
Y
I
Q
L
V
S
S
P
S
F
S
L
D
Frog
Xenopus laevis
NP_001087589
685
78447
V662
Q
K
K
R
L
G
N
V
L
L
Q
S
S
R
A
Zebra Danio
Brachydanio rerio
Q9W6G6
764
87841
S723
K
D
Y
L
R
M
L
S
G
P
A
R
S
L
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24322
850
95478
N774
K
K
A
V
N
N
T
N
T
R
N
R
S
L
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98.8
96.1
N.A.
92.9
54.3
N.A.
85.2
84
66.1
62.6
N.A.
27.6
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
99.3
98.8
N.A.
96.6
73.8
N.A.
90.9
92
76.5
79
N.A.
46.2
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
26.6
N.A.
100
80
6.6
60
N.A.
26.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
73.3
N.A.
100
100
13.3
80
N.A.
46.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
0
0
0
10
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
82
0
0
0
0
0
0
0
0
0
0
0
0
73
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
10
0
0
0
0
0
0
0
0
64
0
0
0
% F
% Gly:
0
0
0
0
0
10
0
0
10
0
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
0
0
0
64
0
55
10
0
0
0
0
0
0
0
0
% I
% Lys:
82
19
10
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
10
10
19
64
0
10
10
0
10
0
82
0
% L
% Met:
0
0
0
10
0
10
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
0
0
0
10
10
10
19
0
0
73
0
10
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
82
0
0
0
0
0
% P
% Gln:
10
0
0
0
73
0
0
0
0
0
10
0
0
0
0
% Q
% Arg:
10
0
0
10
10
0
0
0
0
10
0
19
0
10
0
% R
% Ser:
0
0
0
0
0
0
0
73
64
0
10
10
91
0
0
% S
% Thr:
0
0
0
0
0
0
10
0
10
0
0
0
0
10
0
% T
% Val:
0
0
0
10
0
0
10
10
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
73
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _