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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UPP2 All Species: 38.79
Human Site: S234 Identified Species: 77.58
UniProt: O95045 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95045 NP_001128570.1 317 35527 S234 D G A L C S F S R E K K L D Y
Chimpanzee Pan troglodytes XP_525947 317 35436 S234 D G A L C S F S R E K K L D Y
Rhesus Macaque Macaca mulatta XP_001089251 317 35573 S234 D G A L C S F S R E K K L D Y
Dog Lupus familis XP_537889 315 33991 T228 D G A L C S Y T E K D K Q D Y
Cat Felis silvestris
Mouse Mus musculus Q8CGR7 320 35737 S234 D G A L C S F S R E K K L D Y
Rat Rattus norvegicus NP_001099951 316 35213 E232 A L C C F S R E K K L D Y L K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506899 306 33807 T224 D G A F C S Y T E E D K Q K Y
Chicken Gallus gallus XP_422171 315 34397 S222 D G A L C S F S N E K K L Q Y
Frog Xenopus laevis NP_001088941 316 35092 S234 D G A L C S F S K E E K F E Y
Zebra Danio Brachydanio rerio NP_956438 313 35069 S230 D G A L C S F S T E E K F E Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651515 347 38658 S235 D G A F C D F S E N E K M A Y
Honey Bee Apis mellifera XP_395069 367 41597 T255 D G A F C E F T E N E K I E Y
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 96.2 61.5 N.A. 86.8 85.1 N.A. 61.2 73.1 71.9 64.9 N.A. 45.5 45.2 N.A. N.A.
Protein Similarity: 100 99.3 97.4 77.9 N.A. 93.7 93 N.A. 76.3 83.2 86.1 81 N.A. 65.7 62.4 N.A. N.A.
P-Site Identity: 100 100 100 60 N.A. 100 6.6 N.A. 53.3 86.6 73.3 73.3 N.A. 53.3 46.6 N.A. N.A.
P-Site Similarity: 100 100 100 80 N.A. 100 20 N.A. 66.6 86.6 93.3 86.6 N.A. 66.6 73.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 92 0 0 0 0 0 0 0 0 0 0 9 0 % A
% Cys: 0 0 9 9 92 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 92 0 0 0 0 9 0 0 0 0 17 9 0 42 0 % D
% Glu: 0 0 0 0 0 9 0 9 34 67 34 0 0 25 0 % E
% Phe: 0 0 0 25 9 0 75 0 0 0 0 0 17 0 0 % F
% Gly: 0 92 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 17 17 42 92 0 9 9 % K
% Leu: 0 9 0 67 0 0 0 0 0 0 9 0 42 9 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 9 17 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 17 9 0 % Q
% Arg: 0 0 0 0 0 0 9 0 34 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 84 0 67 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 25 9 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 17 0 0 0 0 0 9 0 92 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _