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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UPP2
All Species:
35.45
Human Site:
Y241
Identified Species:
70.91
UniProt:
O95045
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95045
NP_001128570.1
317
35527
Y241
S
R
E
K
K
L
D
Y
L
K
R
A
F
K
A
Chimpanzee
Pan troglodytes
XP_525947
317
35436
Y241
S
R
E
K
K
L
D
Y
L
K
R
A
Y
K
A
Rhesus Macaque
Macaca mulatta
XP_001089251
317
35573
Y241
S
R
E
K
K
L
D
Y
L
K
R
A
Y
K
A
Dog
Lupus familis
XP_537889
315
33991
Y235
T
E
K
D
K
Q
D
Y
L
R
A
A
H
A
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8CGR7
320
35737
Y241
S
R
E
K
K
L
D
Y
L
K
R
A
Y
R
A
Rat
Rattus norvegicus
NP_001099951
316
35213
K239
E
K
K
L
D
Y
L
K
R
A
Y
K
A
G
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506899
306
33807
Y231
T
E
E
D
K
Q
K
Y
L
K
A
A
C
D
A
Chicken
Gallus gallus
XP_422171
315
34397
Y229
S
N
E
K
K
L
Q
Y
L
K
R
A
H
D
A
Frog
Xenopus laevis
NP_001088941
316
35092
Y241
S
K
E
E
K
F
E
Y
L
Q
R
A
F
S
S
Zebra Danio
Brachydanio rerio
NP_956438
313
35069
Y237
S
T
E
E
K
F
E
Y
L
R
K
A
S
K
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651515
347
38658
Y242
S
E
N
E
K
M
A
Y
L
E
K
L
R
E
N
Honey Bee
Apis mellifera
XP_395069
367
41597
Y262
T
E
N
E
K
I
E
Y
L
N
K
L
H
K
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
96.2
61.5
N.A.
86.8
85.1
N.A.
61.2
73.1
71.9
64.9
N.A.
45.5
45.2
N.A.
N.A.
Protein Similarity:
100
99.3
97.4
77.9
N.A.
93.7
93
N.A.
76.3
83.2
86.1
81
N.A.
65.7
62.4
N.A.
N.A.
P-Site Identity:
100
93.3
93.3
40
N.A.
86.6
0
N.A.
46.6
73.3
53.3
53.3
N.A.
26.6
33.3
N.A.
N.A.
P-Site Similarity:
100
100
100
60
N.A.
100
13.3
N.A.
53.3
73.3
86.6
80
N.A.
60
66.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
9
0
0
9
17
75
9
9
75
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% C
% Asp:
0
0
0
17
9
0
42
0
0
0
0
0
0
17
0
% D
% Glu:
9
34
67
34
0
0
25
0
0
9
0
0
0
9
0
% E
% Phe:
0
0
0
0
0
17
0
0
0
0
0
0
17
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
25
0
0
% H
% Ile:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
17
17
42
92
0
9
9
0
50
25
9
0
42
0
% K
% Leu:
0
0
0
9
0
42
9
0
92
0
0
17
0
0
0
% L
% Met:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
17
0
0
0
0
0
0
9
0
0
0
0
9
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
17
9
0
0
9
0
0
0
0
0
% Q
% Arg:
0
34
0
0
0
0
0
0
9
17
50
0
9
9
0
% R
% Ser:
67
0
0
0
0
0
0
0
0
0
0
0
9
9
9
% S
% Thr:
25
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
9
0
92
0
0
9
0
25
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _