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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UPP2 All Species: 36.67
Human Site: Y297 Identified Species: 73.33
UniProt: O95045 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95045 NP_001128570.1 317 35527 Y297 P H D V L V E Y Q Q R P Q L L
Chimpanzee Pan troglodytes XP_525947 317 35436 Y297 P H D V L V E Y Q Q R P Q L L
Rhesus Macaque Macaca mulatta XP_001089251 317 35573 Y297 P H D V L V E Y Q Q W P Q L L
Dog Lupus familis XP_537889 315 33991 Y291 P H D V L V K Y Q Q R P Q R L
Cat Felis silvestris
Mouse Mus musculus Q8CGR7 320 35737 Y297 S H D V L V E Y Q Q R P Q L L
Rat Rattus norvegicus NP_001099951 316 35213 Y293 S H D V L V E Y Q Q R P Q L L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506899 306 33807 Y287 S H E V L V E Y Q Q R P Q K L
Chicken Gallus gallus XP_422171 315 34397 Y285 S H E V L Q E Y Q Q R P Q R L
Frog Xenopus laevis NP_001088941 316 35092 Y297 S H E T L T E Y Q K R P Q Q L
Zebra Danio Brachydanio rerio NP_956438 313 35069 Y293 P H D I L M E Y Q Q R P Q R L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651515 347 38658 W298 P K E V M N E W Q A R P Q I L
Honey Bee Apis mellifera XP_395069 367 41597 W318 P K E V L D E W Q I R P Q E L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 96.2 61.5 N.A. 86.8 85.1 N.A. 61.2 73.1 71.9 64.9 N.A. 45.5 45.2 N.A. N.A.
Protein Similarity: 100 99.3 97.4 77.9 N.A. 93.7 93 N.A. 76.3 83.2 86.1 81 N.A. 65.7 62.4 N.A. N.A.
P-Site Identity: 100 100 93.3 86.6 N.A. 93.3 93.3 N.A. 80 73.3 60 80 N.A. 53.3 60 N.A. N.A.
P-Site Similarity: 100 100 93.3 93.3 N.A. 93.3 93.3 N.A. 86.6 80 73.3 93.3 N.A. 80 73.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 59 0 0 9 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 42 0 0 0 92 0 0 0 0 0 0 9 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 84 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 9 0 0 0 0 0 9 0 0 0 9 0 % I
% Lys: 0 17 0 0 0 0 9 0 0 9 0 0 0 9 0 % K
% Leu: 0 0 0 0 92 0 0 0 0 0 0 0 0 42 100 % L
% Met: 0 0 0 0 9 9 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % N
% Pro: 59 0 0 0 0 0 0 0 0 0 0 100 0 0 0 % P
% Gln: 0 0 0 0 0 9 0 0 100 75 0 0 100 9 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 92 0 0 25 0 % R
% Ser: 42 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 9 0 9 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 84 0 59 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 17 0 0 9 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 84 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _