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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DIRAS1
All Species:
22.12
Human Site:
T126
Identified Species:
37.44
UniProt:
O95057
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95057
NP_660156.1
198
22329
T126
V
G
N
K
C
D
E
T
Q
R
E
V
D
T
R
Chimpanzee
Pan troglodytes
XP_001142084
196
21944
L127
G
N
K
C
D
E
S
L
S
R
E
V
Q
S
S
Rhesus Macaque
Macaca mulatta
XP_001099006
198
22268
T126
V
G
N
K
C
D
E
T
Q
R
E
V
D
T
R
Dog
Lupus familis
XP_542186
198
22352
T126
V
G
N
K
C
D
E
T
Q
R
E
V
D
T
R
Cat
Felis silvestris
Mouse
Mus musculus
Q91Z61
198
22246
T126
V
G
N
K
C
D
E
T
Q
R
E
V
H
T
R
Rat
Rattus norvegicus
Q62636
184
20779
G115
D
V
P
M
I
L
V
G
N
K
C
D
L
E
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515276
297
31728
T193
V
G
N
K
C
D
E
T
Q
R
E
V
D
T
R
Chicken
Gallus gallus
XP_423026
199
22563
Q127
G
N
K
N
D
E
N
Q
N
R
E
V
E
S
S
Frog
Xenopus laevis
Q7ZXH7
184
20815
G115
D
V
P
M
I
L
V
G
N
K
C
D
L
E
D
Zebra Danio
Brachydanio rerio
Q6TEN1
184
20809
G115
D
V
P
M
I
L
V
G
N
K
C
D
L
E
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P08645
184
20845
G115
D
V
P
M
V
L
V
G
N
K
C
D
L
E
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780973
198
22635
P126
V
G
N
K
C
D
D
P
N
R
E
V
S
I
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P13856
272
30372
T203
P
S
S
A
K
Q
D
T
K
Q
S
N
N
K
Q
Red Bread Mold
Neurospora crassa
Q01387
229
25331
T146
G
N
K
S
D
R
V
T
E
R
E
V
S
T
Q
Conservation
Percent
Protein Identity:
100
71.7
99.4
97.4
N.A.
93.9
39.9
N.A.
55.2
79.9
39.9
39.9
N.A.
39.3
N.A.
N.A.
74.7
Protein Similarity:
100
84.3
99.4
98.9
N.A.
97.4
64.1
N.A.
60.9
90.9
64.1
64.6
N.A.
64.1
N.A.
N.A.
87.8
P-Site Identity:
100
20
100
100
N.A.
93.3
0
N.A.
100
20
0
0
N.A.
0
N.A.
N.A.
60
P-Site Similarity:
100
33.3
100
100
N.A.
93.3
6.6
N.A.
100
40
6.6
6.6
N.A.
6.6
N.A.
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.4
33.6
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
51.8
51.9
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
33.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
8
43
0
0
0
0
0
29
0
0
0
0
% C
% Asp:
29
0
0
0
22
43
15
0
0
0
0
29
29
0
22
% D
% Glu:
0
0
0
0
0
15
36
0
8
0
65
0
8
29
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
22
43
0
0
0
0
0
29
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
0
0
0
0
22
0
0
0
0
0
0
0
0
8
0
% I
% Lys:
0
0
22
43
8
0
0
0
8
29
0
0
0
8
0
% K
% Leu:
0
0
0
0
0
29
0
8
0
0
0
0
29
0
0
% L
% Met:
0
0
0
29
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
22
43
8
0
0
8
0
43
0
0
8
8
0
0
% N
% Pro:
8
0
29
0
0
0
0
8
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
8
0
8
36
8
0
0
8
0
22
% Q
% Arg:
0
0
0
0
0
8
0
0
0
65
0
0
0
0
36
% R
% Ser:
0
8
8
8
0
0
8
0
8
0
8
0
15
15
15
% S
% Thr:
0
0
0
0
0
0
0
50
0
0
0
0
0
43
0
% T
% Val:
43
29
0
0
8
0
36
0
0
0
0
65
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _