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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DIRAS1
All Species:
9.09
Human Site:
T188
Identified Species:
15.38
UniProt:
O95057
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.31
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95057
NP_660156.1
198
22329
T188
R
S
G
K
Q
K
R
T
D
R
V
K
G
K
C
Chimpanzee
Pan troglodytes
XP_001142084
196
21944
I187
E
E
N
S
I
K
R
I
E
P
Q
R
K
C
V
Rhesus Macaque
Macaca mulatta
XP_001099006
198
22268
T188
R
S
G
K
Q
K
R
T
D
R
V
K
G
K
C
Dog
Lupus familis
XP_542186
198
22352
T188
R
A
S
K
Q
K
R
T
D
R
V
K
G
K
C
Cat
Felis silvestris
Mouse
Mus musculus
Q91Z61
198
22246
A188
R
S
S
K
Q
K
R
A
D
R
I
K
G
K
C
Rat
Rattus norvegicus
Q62636
184
20779
A175
K
T
P
V
P
G
K
A
R
K
K
S
S
C
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515276
297
31728
T255
A
Q
A
P
P
G
D
T
P
S
R
P
A
G
G
Chicken
Gallus gallus
XP_423026
199
22563
K189
K
S
K
Q
Q
K
R
K
E
K
L
K
G
K
C
Frog
Xenopus laevis
Q7ZXH7
184
20815
A175
K
T
P
V
P
G
K
A
R
K
K
S
T
C
H
Zebra Danio
Brachydanio rerio
Q6TEN1
184
20809
P175
K
T
P
V
T
G
K
P
R
K
K
S
T
C
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P08645
184
20845
K175
S
P
E
K
K
Q
K
K
P
K
K
S
L
C
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780973
198
22635
R188
K
T
K
S
Q
K
R
R
E
K
L
K
G
K
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P13856
272
30372
K263
T
S
Q
Q
K
K
K
K
K
N
A
S
T
C
T
Red Bread Mold
Neurospora crassa
Q01387
229
25331
P219
K
Y
S
G
T
E
K
P
K
R
P
R
G
K
C
Conservation
Percent
Protein Identity:
100
71.7
99.4
97.4
N.A.
93.9
39.9
N.A.
55.2
79.9
39.9
39.9
N.A.
39.3
N.A.
N.A.
74.7
Protein Similarity:
100
84.3
99.4
98.9
N.A.
97.4
64.1
N.A.
60.9
90.9
64.1
64.6
N.A.
64.1
N.A.
N.A.
87.8
P-Site Identity:
100
13.3
100
86.6
N.A.
80
0
N.A.
6.6
53.3
0
0
N.A.
6.6
N.A.
N.A.
46.6
P-Site Similarity:
100
26.6
100
93.3
N.A.
86.6
26.6
N.A.
6.6
86.6
26.6
26.6
N.A.
33.3
N.A.
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.4
33.6
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
51.8
51.9
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
26.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
53.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
0
0
0
0
22
0
0
8
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
43
50
% C
% Asp:
0
0
0
0
0
0
8
0
29
0
0
0
0
0
0
% D
% Glu:
8
8
8
0
0
8
0
0
22
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
15
8
0
29
0
0
0
0
0
0
50
8
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
0
0
0
8
0
0
8
0
0
8
0
0
0
0
% I
% Lys:
43
0
15
36
15
58
43
22
15
43
29
43
8
50
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
15
0
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
0
0
0
0
8
0
0
0
0
0
% N
% Pro:
0
8
22
8
22
0
0
15
15
8
8
8
0
0
0
% P
% Gln:
0
8
8
15
43
8
0
0
0
0
8
0
0
0
15
% Q
% Arg:
29
0
0
0
0
0
50
8
22
36
8
15
0
0
0
% R
% Ser:
8
36
22
15
0
0
0
0
0
8
0
36
8
0
0
% S
% Thr:
8
29
0
0
15
0
0
29
0
0
0
0
22
0
8
% T
% Val:
0
0
0
22
0
0
0
0
0
0
22
0
0
0
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _