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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DIRAS1
All Species:
35.15
Human Site:
Y44
Identified Species:
59.49
UniProt:
O95057
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95057
NP_660156.1
198
22329
Y44
I
P
T
I
E
D
T
Y
R
Q
V
I
S
C
D
Chimpanzee
Pan troglodytes
XP_001142084
196
21944
Y44
I
P
T
V
E
D
T
Y
R
Q
V
I
S
C
D
Rhesus Macaque
Macaca mulatta
XP_001099006
198
22268
Y44
I
P
T
I
E
D
T
Y
R
Q
V
I
S
C
D
Dog
Lupus familis
XP_542186
198
22352
Y44
I
P
T
I
E
D
T
Y
R
Q
V
I
S
C
D
Cat
Felis silvestris
Mouse
Mus musculus
Q91Z61
198
22246
Y44
I
P
T
I
E
D
T
Y
R
Q
V
I
S
C
D
Rat
Rattus norvegicus
Q62636
184
20779
P34
I
F
V
E
K
Y
D
P
T
I
E
D
S
Y
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515276
297
31728
Y111
I
P
T
I
E
D
T
Y
R
Q
V
I
S
C
D
Chicken
Gallus gallus
XP_423026
199
22563
Y44
I
P
T
I
E
D
T
Y
R
Q
V
I
S
C
D
Frog
Xenopus laevis
Q7ZXH7
184
20815
P34
I
F
V
E
K
Y
D
P
T
I
E
D
S
Y
R
Zebra Danio
Brachydanio rerio
Q6TEN1
184
20809
P34
I
F
V
E
K
Y
D
P
T
I
E
D
S
Y
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P08645
184
20845
P34
I
F
V
E
K
Y
D
P
T
I
E
D
S
Y
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780973
198
22635
Y44
I
P
T
I
E
D
T
Y
R
Q
V
I
S
C
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P13856
272
30372
R87
L
V
Y
S
V
T
D
R
Q
S
L
E
E
L
M
Red Bread Mold
Neurospora crassa
Q01387
229
25331
Y45
D
P
T
I
E
D
S
Y
R
K
Q
V
V
I
D
Conservation
Percent
Protein Identity:
100
71.7
99.4
97.4
N.A.
93.9
39.9
N.A.
55.2
79.9
39.9
39.9
N.A.
39.3
N.A.
N.A.
74.7
Protein Similarity:
100
84.3
99.4
98.9
N.A.
97.4
64.1
N.A.
60.9
90.9
64.1
64.6
N.A.
64.1
N.A.
N.A.
87.8
P-Site Identity:
100
93.3
100
100
N.A.
100
13.3
N.A.
100
100
13.3
13.3
N.A.
13.3
N.A.
N.A.
93.3
P-Site Similarity:
100
100
100
100
N.A.
100
20
N.A.
100
100
20
20
N.A.
20
N.A.
N.A.
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.4
33.6
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
51.8
51.9
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
53.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
73.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
58
0
% C
% Asp:
8
0
0
0
0
65
36
0
0
0
0
29
0
0
58
% D
% Glu:
0
0
0
29
65
0
0
0
0
0
29
8
8
0
0
% E
% Phe:
0
29
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
86
0
0
58
0
0
0
0
0
29
0
58
0
8
0
% I
% Lys:
0
0
0
0
29
0
0
0
0
8
0
0
0
0
0
% K
% Leu:
8
0
0
0
0
0
0
0
0
0
8
0
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% N
% Pro:
0
65
0
0
0
0
0
29
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
8
58
8
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
8
65
0
0
0
0
0
29
% R
% Ser:
0
0
0
8
0
0
8
0
0
8
0
0
86
0
0
% S
% Thr:
0
0
65
0
0
8
58
0
29
0
0
0
0
0
0
% T
% Val:
0
8
29
8
8
0
0
0
0
0
58
8
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
29
0
65
0
0
0
0
0
29
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _