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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DIRAS1 All Species: 33.94
Human Site: Y8 Identified Species: 57.44
UniProt: O95057 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95057 NP_660156.1 198 22329 Y8 M P E Q S N D Y R V V V F G A
Chimpanzee Pan troglodytes XP_001142084 196 21944 Y8 M P E Q S N D Y R V A V F G A
Rhesus Macaque Macaca mulatta XP_001099006 198 22268 Y8 M P E Q S N D Y R V V V F G A
Dog Lupus familis XP_542186 198 22352 Y8 M P E Q S N D Y R V V V F G A
Cat Felis silvestris
Mouse Mus musculus Q91Z61 198 22246 Y8 M P E Q S N D Y R V V V F G A
Rat Rattus norvegicus Q62636 184 20779
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515276 297 31728 Y75 M P E Q S N D Y R V V V F G A
Chicken Gallus gallus XP_423026 199 22563 Y8 M P E Q S N D Y R V V V F G A
Frog Xenopus laevis Q7ZXH7 184 20815
Zebra Danio Brachydanio rerio Q6TEN1 184 20809
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P08645 184 20845
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780973 198 22635 Y8 M P E Q S N D Y R V V V F G A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P13856 272 30372 F51 I E I D N K V F D L E I L D T
Red Bread Mold Neurospora crassa Q01387 229 25331 Y9 V G N K Q V L Y K L V V L G D
Conservation
Percent
Protein Identity: 100 71.7 99.4 97.4 N.A. 93.9 39.9 N.A. 55.2 79.9 39.9 39.9 N.A. 39.3 N.A. N.A. 74.7
Protein Similarity: 100 84.3 99.4 98.9 N.A. 97.4 64.1 N.A. 60.9 90.9 64.1 64.6 N.A. 64.1 N.A. N.A. 87.8
P-Site Identity: 100 93.3 100 100 N.A. 100 0 N.A. 100 100 0 0 N.A. 0 N.A. N.A. 100
P-Site Similarity: 100 93.3 100 100 N.A. 100 0 N.A. 100 100 0 0 N.A. 0 N.A. N.A. 100
Percent
Protein Identity: N.A. N.A. N.A. N.A. 33.4 33.6
Protein Similarity: N.A. N.A. N.A. N.A. 51.8 51.9
P-Site Identity: N.A. N.A. N.A. N.A. 0 26.6
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 53.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 58 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 8 0 0 58 0 8 0 0 0 0 8 8 % D
% Glu: 0 8 58 0 0 0 0 0 0 0 8 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 8 0 0 0 0 58 0 0 % F
% Gly: 0 8 0 0 0 0 0 0 0 0 0 0 0 65 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 8 0 8 0 0 0 0 0 0 0 0 8 0 0 0 % I
% Lys: 0 0 0 8 0 8 0 0 8 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 8 0 0 15 0 0 15 0 0 % L
% Met: 58 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 8 0 8 58 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 58 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 58 8 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 58 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 58 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % T
% Val: 8 0 0 0 0 8 8 0 0 58 58 65 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 65 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _