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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCNK2
All Species:
33.33
Human Site:
Y281
Identified Species:
66.67
UniProt:
O95069
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95069
NP_001017424.1
426
47093
Y281
A
G
G
S
D
I
E
Y
L
D
F
Y
K
P
V
Chimpanzee
Pan troglodytes
XP_514195
421
46737
Y276
A
G
G
S
D
I
E
Y
L
D
F
Y
K
P
V
Rhesus Macaque
Macaca mulatta
XP_001083327
781
86054
Y535
G
G
N
A
G
I
N
Y
R
E
W
Y
K
P
L
Dog
Lupus familis
XP_849278
422
46753
Y277
A
G
G
S
D
I
E
Y
L
D
F
Y
K
P
V
Cat
Felis silvestris
Mouse
Mus musculus
P97438
411
45279
Y266
A
G
G
S
D
I
E
Y
L
D
F
Y
K
P
V
Rat
Rattus norvegicus
Q9JIS4
538
59782
Y292
G
G
N
A
G
I
N
Y
R
E
W
Y
K
P
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510388
626
67934
Y481
A
G
G
S
D
I
E
Y
L
D
F
Y
K
P
V
Chicken
Gallus gallus
XP_001234270
413
45532
Y268
A
G
G
S
D
I
E
Y
L
D
F
Y
K
P
V
Frog
Xenopus laevis
Q63ZI0
374
42700
A237
V
G
L
T
V
I
G
A
F
L
N
L
V
V
L
Zebra Danio
Brachydanio rerio
XP_688186
490
54952
Y343
A
G
G
S
E
I
E
Y
L
D
Y
Y
K
P
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O17185
329
36973
C192
Y
F
D
A
V
Y
Y
C
F
V
T
L
T
T
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40310
691
77389
R430
G
Y
G
D
Y
A
P
R
T
G
A
G
R
A
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.1
36.6
95.5
N.A.
92.9
49.8
N.A.
65.1
90.8
24.4
65
N.A.
N.A.
N.A.
26
N.A.
Protein Similarity:
100
97.8
44.8
97.4
N.A.
95.5
62.4
N.A.
66.7
94.3
44.1
75.3
N.A.
N.A.
N.A.
41.7
N.A.
P-Site Identity:
100
100
40
100
N.A.
100
40
N.A.
100
100
13.3
80
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
100
66.6
100
N.A.
100
66.6
N.A.
100
100
26.6
100
N.A.
N.A.
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
37.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
59
0
0
25
0
9
0
9
0
0
9
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
9
50
0
0
0
0
59
0
0
0
0
0
% D
% Glu:
0
0
0
0
9
0
59
0
0
17
0
0
0
0
0
% E
% Phe:
0
9
0
0
0
0
0
0
17
0
50
0
0
0
9
% F
% Gly:
25
84
67
0
17
0
9
0
0
9
0
9
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
84
0
0
0
0
0
0
0
0
17
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
75
0
0
% K
% Leu:
0
0
9
0
0
0
0
0
59
9
0
17
0
0
25
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
17
0
0
0
17
0
0
0
9
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
9
0
0
0
0
0
0
75
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
9
17
0
0
0
9
0
0
% R
% Ser:
0
0
0
59
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
9
0
0
0
0
9
0
9
0
9
9
0
% T
% Val:
9
0
0
0
17
0
0
0
0
9
0
0
9
9
50
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
17
0
0
0
0
% W
% Tyr:
9
9
0
0
9
9
9
75
0
0
9
75
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _