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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCNK2
All Species:
22.12
Human Site:
Y406
Identified Species:
44.24
UniProt:
O95069
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95069
NP_001017424.1
426
47093
Y406
L
L
K
T
E
S
I
Y
L
N
G
L
T
P
H
Chimpanzee
Pan troglodytes
XP_514195
421
46737
Y401
L
L
K
T
E
S
I
Y
L
N
G
L
T
P
H
Rhesus Macaque
Macaca mulatta
XP_001083327
781
86054
N660
A
S
S
Q
E
S
I
N
N
R
P
N
N
L
R
Dog
Lupus familis
XP_849278
422
46753
Y402
L
L
K
T
D
S
I
Y
L
N
G
L
T
P
H
Cat
Felis silvestris
Mouse
Mus musculus
P97438
411
45279
Y391
L
L
K
A
E
S
I
Y
L
N
G
L
T
P
H
Rat
Rattus norvegicus
Q9JIS4
538
59782
N417
A
S
S
Q
E
S
I
N
N
R
P
N
N
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510388
626
67934
Y606
L
T
K
T
D
S
I
Y
L
N
G
L
T
P
H
Chicken
Gallus gallus
XP_001234270
413
45532
Y393
L
T
K
T
D
S
I
Y
M
N
G
L
T
P
H
Frog
Xenopus laevis
Q63ZI0
374
42700
T362
S
P
G
L
H
S
F
T
D
K
H
R
L
M
K
Zebra Danio
Brachydanio rerio
XP_688186
490
54952
L468
T
L
T
K
N
G
S
L
Y
L
N
G
L
T
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O17185
329
36973
P317
H
T
E
P
H
G
G
P
P
T
F
S
G
M
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40310
691
77389
A555
S
F
S
S
L
S
K
A
S
S
P
E
G
I
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.1
36.6
95.5
N.A.
92.9
49.8
N.A.
65.1
90.8
24.4
65
N.A.
N.A.
N.A.
26
N.A.
Protein Similarity:
100
97.8
44.8
97.4
N.A.
95.5
62.4
N.A.
66.7
94.3
44.1
75.3
N.A.
N.A.
N.A.
41.7
N.A.
P-Site Identity:
100
100
20
93.3
N.A.
93.3
20
N.A.
86.6
80
6.6
6.6
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
100
20
100
N.A.
93.3
20
N.A.
93.3
93.3
6.6
6.6
N.A.
N.A.
N.A.
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
37.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
0
0
9
0
0
0
9
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
25
0
0
0
9
0
0
0
0
0
0
% D
% Glu:
0
0
9
0
42
0
0
0
0
0
0
9
0
0
0
% E
% Phe:
0
9
0
0
0
0
9
0
0
0
9
0
0
0
0
% F
% Gly:
0
0
9
0
0
17
9
0
0
0
50
9
17
0
0
% G
% His:
9
0
0
0
17
0
0
0
0
0
9
0
0
0
50
% H
% Ile:
0
0
0
0
0
0
67
0
0
0
0
0
0
9
0
% I
% Lys:
0
0
50
9
0
0
9
0
0
9
0
0
0
0
9
% K
% Leu:
50
42
0
9
9
0
0
9
42
9
0
50
17
17
9
% L
% Met:
0
0
0
0
0
0
0
0
9
0
0
0
0
17
0
% M
% Asn:
0
0
0
0
9
0
0
17
17
50
9
17
17
0
0
% N
% Pro:
0
9
0
9
0
0
0
9
9
0
25
0
0
50
9
% P
% Gln:
0
0
0
17
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
17
0
9
0
0
17
% R
% Ser:
17
17
25
9
0
84
9
0
9
9
0
9
0
0
0
% S
% Thr:
9
25
9
42
0
0
0
9
0
9
0
0
50
9
9
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
50
9
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _