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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRSS23
All Species:
11.52
Human Site:
S120
Identified Species:
28.15
UniProt:
O95084
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95084
NP_009104.1
383
43001
S120
A
Q
H
R
D
S
G
S
S
G
K
S
R
R
K
Chimpanzee
Pan troglodytes
XP_508909
464
51444
S201
A
Q
H
R
D
S
G
S
S
G
K
S
R
R
K
Rhesus Macaque
Macaca mulatta
Q1WK23
383
42864
S120
A
Q
H
R
D
S
G
S
S
G
K
S
R
R
K
Dog
Lupus familis
XP_542268
379
42356
R121
Q
E
S
S
G
K
A
R
R
K
R
Q
I
Y
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9D6X6
382
43053
A119
A
R
G
R
D
S
E
A
T
G
R
S
R
R
K
Rat
Rattus norvegicus
Q6AY61
383
43141
A120
A
R
S
R
D
S
E
A
A
G
K
S
R
R
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511792
377
42006
A120
G
G
E
A
R
P
R
A
K
R
Q
I
Y
G
Y
Chicken
Gallus gallus
XP_417210
355
40254
Y105
T
K
R
Q
I
Y
G
Y
D
S
R
F
S
I
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_692384
373
42547
T115
D
P
P
P
R
Q
L
T
S
R
H
K
R
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796599
311
35578
R69
A
V
V
G
A
N
T
R
F
P
I
D
D
R
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82.3
98.9
93.7
N.A.
90.8
91.3
N.A.
81.1
82.2
N.A.
51.4
N.A.
N.A.
N.A.
N.A.
33.6
Protein Similarity:
100
82.5
99.4
95.8
N.A.
94.5
94.2
N.A.
89.5
87.2
N.A.
68.1
N.A.
N.A.
N.A.
N.A.
51.4
P-Site Identity:
100
100
100
0
N.A.
60
66.6
N.A.
0
6.6
N.A.
20
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
100
100
13.3
N.A.
86.6
86.6
N.A.
13.3
26.6
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
60
0
0
10
10
0
10
30
10
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
50
0
0
0
10
0
0
10
10
0
0
% D
% Glu:
0
10
10
0
0
0
20
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
10
0
0
10
0
0
10
% F
% Gly:
10
10
10
10
10
0
40
0
0
50
0
0
0
10
10
% G
% His:
0
0
30
0
0
0
0
0
0
0
10
0
0
0
0
% H
% Ile:
0
0
0
0
10
0
0
0
0
0
10
10
10
10
0
% I
% Lys:
0
10
0
0
0
10
0
0
10
10
40
10
0
0
70
% K
% Leu:
0
0
0
0
0
0
10
0
0
0
0
0
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
10
10
10
0
10
0
0
0
10
0
0
0
0
0
% P
% Gln:
10
30
0
10
0
10
0
0
0
0
10
10
0
0
0
% Q
% Arg:
0
20
10
50
20
0
10
20
10
20
30
0
60
60
0
% R
% Ser:
0
0
20
10
0
50
0
30
40
10
0
50
10
0
0
% S
% Thr:
10
0
0
0
0
0
10
10
10
0
0
0
0
0
0
% T
% Val:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
10
0
0
0
0
10
10
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _