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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRSS23
All Species:
19.09
Human Site:
S138
Identified Species:
46.67
UniProt:
O95084
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95084
NP_009104.1
383
43001
S138
Y
G
Y
D
S
R
F
S
I
F
G
K
D
F
L
Chimpanzee
Pan troglodytes
XP_508909
464
51444
S219
Y
G
Y
D
S
R
F
S
I
F
G
K
D
F
L
Rhesus Macaque
Macaca mulatta
Q1WK23
383
42864
S138
Y
G
Y
D
S
R
F
S
I
F
G
K
D
F
L
Dog
Lupus familis
XP_542268
379
42356
D139
R
F
S
I
F
G
K
D
F
L
L
N
Y
P
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9D6X6
382
43053
S137
Y
G
Y
D
G
R
F
S
I
F
G
K
D
F
L
Rat
Rattus norvegicus
Q6AY61
383
43141
S138
Y
G
Y
D
G
R
F
S
I
F
G
K
D
F
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511792
377
42006
F138
F
S
I
F
G
K
D
F
L
L
N
Y
P
F
S
Chicken
Gallus gallus
XP_417210
355
40254
S123
F
L
L
N
Y
P
F
S
T
S
V
K
L
S
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_692384
373
42547
N133
Y
G
A
D
G
R
F
N
I
R
G
D
H
F
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796599
311
35578
V87
K
E
P
F
S
A
A
V
K
L
S
T
G
C
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82.3
98.9
93.7
N.A.
90.8
91.3
N.A.
81.1
82.2
N.A.
51.4
N.A.
N.A.
N.A.
N.A.
33.6
Protein Similarity:
100
82.5
99.4
95.8
N.A.
94.5
94.2
N.A.
89.5
87.2
N.A.
68.1
N.A.
N.A.
N.A.
N.A.
51.4
P-Site Identity:
100
100
100
0
N.A.
93.3
93.3
N.A.
6.6
20
N.A.
60
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
0
N.A.
93.3
93.3
N.A.
26.6
33.3
N.A.
66.6
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
10
10
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% C
% Asp:
0
0
0
60
0
0
10
10
0
0
0
10
50
0
0
% D
% Glu:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
20
10
0
20
10
0
70
10
10
50
0
0
0
70
10
% F
% Gly:
0
60
0
0
40
10
0
0
0
0
60
0
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
0
10
10
0
0
0
0
60
0
0
0
0
0
0
% I
% Lys:
10
0
0
0
0
10
10
0
10
0
0
60
0
0
0
% K
% Leu:
0
10
10
0
0
0
0
0
10
30
10
0
10
0
60
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
0
10
0
0
10
10
0
0
0
% N
% Pro:
0
0
10
0
0
10
0
0
0
0
0
0
10
10
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
10
0
0
0
0
60
0
0
0
10
0
0
0
0
0
% R
% Ser:
0
10
10
0
40
0
0
60
0
10
10
0
0
10
20
% S
% Thr:
0
0
0
0
0
0
0
0
10
0
0
10
0
0
10
% T
% Val:
0
0
0
0
0
0
0
10
0
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
60
0
50
0
10
0
0
0
0
0
0
10
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _