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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NKX2-2
All Species:
13.03
Human Site:
S101
Identified Species:
26.06
UniProt:
O95096
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95096
NP_002500.1
273
30133
S101
A
P
P
Q
D
S
S
S
K
S
P
E
P
S
A
Chimpanzee
Pan troglodytes
XP_519662
366
38728
P156
D
A
E
R
M
G
E
P
Q
P
G
L
S
A
A
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_542867
273
30061
S101
A
A
P
Q
D
S
S
S
K
S
P
E
P
S
A
Cat
Felis silvestris
Mouse
Mus musculus
P42586
273
30107
S101
A
P
P
Q
D
S
S
S
K
S
P
E
P
S
A
Rat
Rattus norvegicus
P23441
372
38536
N93
Y
C
N
G
N
L
G
N
M
S
E
L
P
P
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90788
294
33054
A89
D
T
A
K
D
S
K
A
D
K
K
E
L
C
A
Frog
Xenopus laevis
P42587
196
22791
L41
P
E
I
R
S
R
F
L
L
L
S
L
Q
K
P
Zebra Danio
Brachydanio rerio
Q90481
269
30288
S100
S
Q
D
T
S
A
K
S
P
E
P
S
A
D
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P22808
723
76404
A478
S
A
G
G
A
P
T
A
H
A
L
H
N
N
N
Honey Bee
Apis mellifera
XP_001121493
260
29654
T85
P
T
G
P
T
L
P
T
T
L
P
Q
P
L
E
Nematode Worm
Caenorhab. elegans
P41936
346
37493
M146
F
P
R
S
E
N
D
M
L
D
N
S
N
T
S
Sea Urchin
Strong. purpuratus
NP_001123283
437
46696
T202
A
T
S
P
T
S
T
T
A
S
A
Q
V
H
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
34.1
N.A.
99.2
N.A.
98.1
32.7
N.A.
N.A.
36.3
54.2
83.8
N.A.
24.8
40.6
29.1
35.7
Protein Similarity:
100
42.9
N.A.
99.6
N.A.
99.2
43.2
N.A.
N.A.
53
60.4
89.3
N.A.
29.3
51.2
42.7
46.2
P-Site Identity:
100
6.6
N.A.
93.3
N.A.
100
13.3
N.A.
N.A.
26.6
0
13.3
N.A.
0
13.3
6.6
20
P-Site Similarity:
100
26.6
N.A.
93.3
N.A.
100
26.6
N.A.
N.A.
40
6.6
26.6
N.A.
33.3
26.6
33.3
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
34
25
9
0
9
9
0
17
9
9
9
0
9
9
42
% A
% Cys:
0
9
0
0
0
0
0
0
0
0
0
0
0
9
0
% C
% Asp:
17
0
9
0
34
0
9
0
9
9
0
0
0
9
0
% D
% Glu:
0
9
9
0
9
0
9
0
0
9
9
34
0
0
25
% E
% Phe:
9
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
17
17
0
9
9
0
0
0
9
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
9
0
0
9
0
9
0
% H
% Ile:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
9
0
0
17
0
25
9
9
0
0
9
0
% K
% Leu:
0
0
0
0
0
17
0
9
17
17
9
25
9
9
0
% L
% Met:
0
0
0
0
9
0
0
9
9
0
0
0
0
0
0
% M
% Asn:
0
0
9
0
9
9
0
9
0
0
9
0
17
9
9
% N
% Pro:
17
25
25
17
0
9
9
9
9
9
42
0
42
9
9
% P
% Gln:
0
9
0
25
0
0
0
0
9
0
0
17
9
0
0
% Q
% Arg:
0
0
9
17
0
9
0
0
0
0
0
0
0
0
0
% R
% Ser:
17
0
9
9
17
42
25
34
0
42
9
17
9
25
9
% S
% Thr:
0
25
0
9
17
0
17
17
9
0
0
0
0
9
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _