KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NKX2-2
All Species:
17.58
Human Site:
S86
Identified Species:
35.15
UniProt:
O95096
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95096
NP_002500.1
273
30133
S86
S
T
E
G
L
Q
Y
S
L
H
G
L
A
A
G
Chimpanzee
Pan troglodytes
XP_519662
366
38728
P141
G
S
E
P
P
G
D
P
C
E
A
V
L
E
M
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_542867
273
30061
S86
S
T
E
G
L
Q
Y
S
L
H
G
L
A
A
G
Cat
Felis silvestris
Mouse
Mus musculus
P42586
273
30107
S86
S
T
E
G
L
Q
Y
S
L
H
G
L
A
A
S
Rat
Rattus norvegicus
P23441
372
38536
L78
T
A
A
G
V
P
Q
L
S
H
S
A
V
G
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90788
294
33054
Y74
A
A
F
P
G
P
Y
Y
V
K
S
Y
G
E
M
Frog
Xenopus laevis
P42587
196
22791
N26
W
L
L
L
R
A
S
N
T
P
C
T
V
L
R
Zebra Danio
Brachydanio rerio
Q90481
269
30288
S85
T
T
D
S
I
Q
Y
S
L
H
G
L
S
A
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P22808
723
76404
L463
V
G
D
A
L
H
T
L
H
G
S
S
G
N
G
Honey Bee
Apis mellifera
XP_001121493
260
29654
P70
N
R
G
T
L
P
P
P
P
P
P
L
L
A
W
Nematode Worm
Caenorhab. elegans
P41936
346
37493
S131
A
S
N
G
I
A
G
S
M
Y
T
L
P
D
Q
Sea Urchin
Strong. purpuratus
NP_001123283
437
46696
S187
S
L
A
Q
N
T
V
S
H
N
S
T
S
S
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
34.1
N.A.
99.2
N.A.
98.1
32.7
N.A.
N.A.
36.3
54.2
83.8
N.A.
24.8
40.6
29.1
35.7
Protein Similarity:
100
42.9
N.A.
99.6
N.A.
99.2
43.2
N.A.
N.A.
53
60.4
89.3
N.A.
29.3
51.2
42.7
46.2
P-Site Identity:
100
6.6
N.A.
100
N.A.
93.3
20
N.A.
N.A.
6.6
0
60
N.A.
13.3
20
20
13.3
P-Site Similarity:
100
20
N.A.
100
N.A.
93.3
33.3
N.A.
N.A.
20
6.6
86.6
N.A.
20
26.6
53.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
17
17
9
0
17
0
0
0
0
9
9
25
42
0
% A
% Cys:
0
0
0
0
0
0
0
0
9
0
9
0
0
0
0
% C
% Asp:
0
0
17
0
0
0
9
0
0
0
0
0
0
9
0
% D
% Glu:
0
0
34
0
0
0
0
0
0
9
0
0
0
17
0
% E
% Phe:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
9
9
42
9
9
9
0
0
9
34
0
17
9
34
% G
% His:
0
0
0
0
0
9
0
0
17
42
0
0
0
0
0
% H
% Ile:
0
0
0
0
17
0
0
0
0
0
0
0
0
0
9
% I
% Lys:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% K
% Leu:
0
17
9
9
42
0
0
17
34
0
0
50
17
9
0
% L
% Met:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
17
% M
% Asn:
9
0
9
0
9
0
0
9
0
9
0
0
0
9
9
% N
% Pro:
0
0
0
17
9
25
9
17
9
17
9
0
9
0
0
% P
% Gln:
0
0
0
9
0
34
9
0
0
0
0
0
0
0
9
% Q
% Arg:
0
9
0
0
9
0
0
0
0
0
0
0
0
0
9
% R
% Ser:
34
17
0
9
0
0
9
50
9
0
34
9
17
9
9
% S
% Thr:
17
34
0
9
0
9
9
0
9
0
9
17
0
0
0
% T
% Val:
9
0
0
0
9
0
9
0
9
0
0
9
17
0
0
% V
% Trp:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% W
% Tyr:
0
0
0
0
0
0
42
9
0
9
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _