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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NKX2-2
All Species:
13.33
Human Site:
T195
Identified Species:
26.67
UniProt:
O95096
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95096
NP_002500.1
273
30133
T195
A
E
K
G
M
E
V
T
P
L
P
S
P
R
R
Chimpanzee
Pan troglodytes
XP_519662
366
38728
A264
Q
D
K
S
L
E
L
A
G
H
P
L
T
P
R
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_542867
273
30061
T195
A
E
K
G
M
E
V
T
P
L
P
S
P
R
R
Cat
Felis silvestris
Mouse
Mus musculus
P42586
273
30107
T195
A
E
K
G
M
E
V
T
P
L
P
S
P
R
R
Rat
Rattus norvegicus
P23441
372
38536
Q228
K
D
K
A
A
Q
Q
Q
L
Q
Q
D
S
G
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90788
294
33054
V186
Q
D
Q
T
L
E
M
V
G
I
P
P
P
R
R
Frog
Xenopus laevis
P42587
196
22791
G132
K
R
A
R
S
E
K
G
M
E
V
T
P
L
P
Zebra Danio
Brachydanio rerio
Q90481
269
30288
T192
A
E
K
G
M
E
V
T
H
L
P
S
P
R
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P22808
723
76404
H612
N
E
K
G
Y
E
G
H
P
G
L
L
H
G
H
Honey Bee
Apis mellifera
XP_001121493
260
29654
I184
E
R
E
H
L
A
S
I
I
R
L
T
P
T
Q
Nematode Worm
Caenorhab. elegans
P41936
346
37493
A256
T
D
K
P
I
N
A
A
L
L
T
T
M
P
N
Sea Urchin
Strong. purpuratus
NP_001123283
437
46696
N309
Q
E
K
G
L
D
L
N
P
L
P
S
P
R
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
34.1
N.A.
99.2
N.A.
98.1
32.7
N.A.
N.A.
36.3
54.2
83.8
N.A.
24.8
40.6
29.1
35.7
Protein Similarity:
100
42.9
N.A.
99.6
N.A.
99.2
43.2
N.A.
N.A.
53
60.4
89.3
N.A.
29.3
51.2
42.7
46.2
P-Site Identity:
100
26.6
N.A.
100
N.A.
100
6.6
N.A.
N.A.
33.3
13.3
93.3
N.A.
33.3
6.6
13.3
66.6
P-Site Similarity:
100
46.6
N.A.
100
N.A.
100
20
N.A.
N.A.
66.6
20
93.3
N.A.
33.3
33.3
33.3
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
34
0
9
9
9
9
9
17
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
34
0
0
0
9
0
0
0
0
0
9
0
0
0
% D
% Glu:
9
50
9
0
0
67
0
0
0
9
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
50
0
0
9
9
17
9
0
0
0
17
9
% G
% His:
0
0
0
9
0
0
0
9
9
9
0
0
9
0
9
% H
% Ile:
0
0
0
0
9
0
0
9
9
9
0
0
0
0
0
% I
% Lys:
17
0
75
0
0
0
9
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
34
0
17
0
17
50
17
17
0
9
0
% L
% Met:
0
0
0
0
34
0
9
0
9
0
0
0
9
0
0
% M
% Asn:
9
0
0
0
0
9
0
9
0
0
0
0
0
0
9
% N
% Pro:
0
0
0
9
0
0
0
0
42
0
59
9
67
17
9
% P
% Gln:
25
0
9
0
0
9
9
9
0
9
9
0
0
0
9
% Q
% Arg:
0
17
0
9
0
0
0
0
0
9
0
0
0
50
59
% R
% Ser:
0
0
0
9
9
0
9
0
0
0
0
42
9
0
0
% S
% Thr:
9
0
0
9
0
0
0
34
0
0
9
25
9
9
0
% T
% Val:
0
0
0
0
0
0
34
9
0
0
9
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _