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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NKX2-2
All Species:
20.62
Human Site:
T6
Identified Species:
41.24
UniProt:
O95096
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95096
NP_002500.1
273
30133
T6
_
_
M
S
L
T
N
T
K
T
G
F
S
V
K
Chimpanzee
Pan troglodytes
XP_519662
366
38728
T72
G
M
L
L
S
P
V
T
S
T
P
F
S
V
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_542867
273
30061
T6
_
_
M
S
L
T
N
T
K
T
G
F
S
V
K
Cat
Felis silvestris
Mouse
Mus musculus
P42586
273
30107
T6
_
_
M
S
L
T
N
T
K
T
G
F
S
V
K
Rat
Rattus norvegicus
P23441
372
38536
H7
_
M
S
M
S
P
K
H
T
T
P
F
S
V
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90788
294
33054
T7
_
M
F
P
S
P
V
T
T
T
P
F
S
V
K
Frog
Xenopus laevis
P42587
196
22791
Zebra Danio
Brachydanio rerio
Q90481
269
30288
T6
_
_
M
S
L
T
N
T
K
T
G
F
S
V
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P22808
723
76404
Q196
D
A
K
V
P
S
S
Q
R
S
G
F
H
I
S
Honey Bee
Apis mellifera
XP_001121493
260
29654
S6
_
_
M
P
R
S
T
S
F
H
I
H
D
I
L
Nematode Worm
Caenorhab. elegans
P41936
346
37493
T11
V
S
A
L
R
A
A
T
P
S
I
A
S
V
S
Sea Urchin
Strong. purpuratus
NP_001123283
437
46696
A72
T
D
A
A
M
N
A
A
K
T
S
F
S
V
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
34.1
N.A.
99.2
N.A.
98.1
32.7
N.A.
N.A.
36.3
54.2
83.8
N.A.
24.8
40.6
29.1
35.7
Protein Similarity:
100
42.9
N.A.
99.6
N.A.
99.2
43.2
N.A.
N.A.
53
60.4
89.3
N.A.
29.3
51.2
42.7
46.2
P-Site Identity:
100
40
N.A.
100
N.A.
100
28.5
N.A.
N.A.
42.8
0
100
N.A.
13.3
7.6
20
40
P-Site Similarity:
100
53.3
N.A.
100
N.A.
100
28.5
N.A.
N.A.
42.8
0
100
N.A.
46.6
30.7
26.6
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
17
9
0
9
17
9
0
0
0
9
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
9
0
0
0
0
0
0
0
0
0
0
9
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
9
0
0
0
0
0
9
0
0
75
0
0
0
% F
% Gly:
9
0
0
0
0
0
0
0
0
0
42
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
9
0
9
0
9
9
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
17
0
0
17
0
% I
% Lys:
0
0
9
0
0
0
9
0
42
0
0
0
0
0
59
% K
% Leu:
0
0
9
17
34
0
0
0
0
0
0
0
0
0
9
% L
% Met:
0
25
42
9
9
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
9
34
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
17
9
25
0
0
9
0
25
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
17
0
0
0
9
0
0
0
0
0
0
% R
% Ser:
0
9
9
34
25
17
9
9
9
17
9
0
75
0
25
% S
% Thr:
9
0
0
0
0
34
9
59
17
67
0
0
0
0
0
% T
% Val:
9
0
0
9
0
0
17
0
0
0
0
0
0
75
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
59
42
0
0
0
0
0
0
0
0
0
0
0
0
0
% _