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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SFRS15
All Species:
23.03
Human Site:
S454
Identified Species:
46.06
UniProt:
O95104
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.36
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95104
NP_001138916.1
1147
125869
S454
R
S
R
S
G
S
R
S
R
R
S
R
H
R
R
Chimpanzee
Pan troglodytes
XP_527544
1370
151436
R522
S
R
S
R
S
G
S
R
K
R
K
H
R
K
R
Rhesus Macaque
Macaca mulatta
XP_001097324
1153
126789
S452
R
S
R
S
G
S
R
S
R
R
S
R
H
R
R
Dog
Lupus familis
XP_533458
1277
141249
K430
R
S
R
S
G
S
R
K
R
K
H
R
K
R
S
Cat
Felis silvestris
Mouse
Mus musculus
NP_849254
1209
131664
S519
R
S
R
S
G
S
R
S
R
R
S
R
H
R
R
Rat
Rattus norvegicus
Q63627
1048
113683
R398
R
S
Q
E
R
R
D
R
E
K
E
R
E
R
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001012840
1092
120824
S442
R
S
R
S
G
S
R
S
R
R
S
R
H
R
R
Frog
Xenopus laevis
NP_001089259
1271
143182
K422
R
S
R
S
G
S
R
K
R
K
H
R
K
R
S
Zebra Danio
Brachydanio rerio
XP_695887
1070
118687
S406
R
S
R
S
N
S
R
S
R
R
M
R
H
R
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001097394
1306
140737
S438
R
R
G
T
R
S
R
S
R
S
R
S
P
R
S
Honey Bee
Apis mellifera
XP_392804
1292
145445
Q458
N
C
E
N
T
R
S
Q
N
R
D
R
D
R
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784032
1759
192667
S433
R
S
R
S
K
S
R
S
K
R
K
R
R
S
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
36.3
97.8
38.9
N.A.
85.4
65.6
N.A.
N.A.
78.9
35.9
49
N.A.
31.6
29.5
N.A.
30
Protein Similarity:
100
49.2
98.1
51.2
N.A.
88.5
72
N.A.
N.A.
84.3
48.3
61.4
N.A.
44
43.3
N.A.
41.9
P-Site Identity:
100
13.3
100
66.6
N.A.
100
33.3
N.A.
N.A.
100
66.6
86.6
N.A.
40
20
N.A.
66.6
P-Site Similarity:
100
26.6
100
73.3
N.A.
100
46.6
N.A.
N.A.
100
73.3
86.6
N.A.
46.6
33.3
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
9
0
0
0
9
0
9
0
0
% D
% Glu:
0
0
9
9
0
0
0
0
9
0
9
0
9
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
9
0
50
9
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
17
9
42
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
9
0
0
17
17
25
17
0
17
9
9
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% M
% Asn:
9
0
0
9
9
0
0
0
9
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% P
% Gln:
0
0
9
0
0
0
0
9
0
0
0
0
0
0
0
% Q
% Arg:
84
17
67
9
17
17
75
17
67
67
9
84
17
84
67
% R
% Ser:
9
75
9
67
9
75
17
59
0
9
34
9
0
9
25
% S
% Thr:
0
0
0
9
9
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _