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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SFRS15
All Species:
14.85
Human Site:
S614
Identified Species:
29.7
UniProt:
O95104
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95104
NP_001138916.1
1147
125869
S614
V
K
P
E
E
L
E
S
F
C
E
G
G
M
L
Chimpanzee
Pan troglodytes
XP_527544
1370
151436
G682
V
K
V
D
D
L
E
G
F
A
E
G
G
M
I
Rhesus Macaque
Macaca mulatta
XP_001097324
1153
126789
S612
V
K
P
E
E
L
E
S
F
C
E
G
G
M
L
Dog
Lupus familis
XP_533458
1277
141249
G589
V
K
V
D
D
L
E
G
F
A
E
G
G
M
I
Cat
Felis silvestris
Mouse
Mus musculus
NP_849254
1209
131664
S679
V
K
A
E
E
L
E
S
F
C
E
G
G
M
L
Rat
Rattus norvegicus
Q63627
1048
113683
K550
D
W
K
G
I
P
K
K
P
E
N
E
V
A
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001012840
1092
120824
S602
V
K
P
E
D
L
E
S
F
C
E
G
G
M
L
Frog
Xenopus laevis
NP_001089259
1271
143182
G581
V
K
V
D
D
L
E
G
F
A
E
G
G
M
I
Zebra Danio
Brachydanio rerio
XP_695887
1070
118687
V564
V
K
M
E
D
L
D
V
F
R
E
G
G
M
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001097394
1306
140737
A598
S
S
D
T
D
F
D
A
L
E
E
G
G
M
F
Honey Bee
Apis mellifera
XP_392804
1292
145445
L617
V
N
V
T
D
Q
D
L
E
L
L
E
E
G
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784032
1759
192667
S552
A
E
Y
G
E
I
I
S
V
E
I
I
G
T
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
36.3
97.8
38.9
N.A.
85.4
65.6
N.A.
N.A.
78.9
35.9
49
N.A.
31.6
29.5
N.A.
30
Protein Similarity:
100
49.2
98.1
51.2
N.A.
88.5
72
N.A.
N.A.
84.3
48.3
61.4
N.A.
44
43.3
N.A.
41.9
P-Site Identity:
100
60
100
60
N.A.
93.3
0
N.A.
N.A.
93.3
60
66.6
N.A.
26.6
6.6
N.A.
20
P-Site Similarity:
100
80
100
80
N.A.
93.3
6.6
N.A.
N.A.
100
80
80
N.A.
46.6
20
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
9
0
0
0
0
9
0
25
0
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
34
0
0
0
0
0
% C
% Asp:
9
0
9
25
59
0
25
0
0
0
0
0
0
0
0
% D
% Glu:
0
9
0
42
34
0
59
0
9
25
75
17
9
0
0
% E
% Phe:
0
0
0
0
0
9
0
0
67
0
0
0
0
0
9
% F
% Gly:
0
0
0
17
0
0
0
25
0
0
0
75
84
9
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
9
9
9
0
0
0
9
9
0
0
25
% I
% Lys:
0
67
9
0
0
0
9
9
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
67
0
9
9
9
9
0
0
0
42
% L
% Met:
0
0
9
0
0
0
0
0
0
0
0
0
0
75
0
% M
% Asn:
0
9
0
0
0
0
0
0
0
0
9
0
0
0
0
% N
% Pro:
0
0
25
0
0
9
0
0
9
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
9
% Q
% Arg:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
9
% R
% Ser:
9
9
0
0
0
0
0
42
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
17
0
0
0
0
0
0
0
0
0
9
0
% T
% Val:
75
0
34
0
0
0
0
9
9
0
0
0
9
0
0
% V
% Trp:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _