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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SFRS15 All Species: 9.09
Human Site: S752 Identified Species: 18.18
UniProt: O95104 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95104 NP_001138916.1 1147 125869 S752 P P I T P P V S I P P P H T P
Chimpanzee Pan troglodytes XP_527544 1370 151436 V800 P P P V P P P V V P P P A I P
Rhesus Macaque Macaca mulatta XP_001097324 1153 126789 S750 P P I T P P V S I P P P H T P
Dog Lupus familis XP_533458 1277 141249 V707 P P P V P P P V V P P P T I P
Cat Felis silvestris
Mouse Mus musculus NP_849254 1209 131664 S817 P P I T P P V S I P P P H T P
Rat Rattus norvegicus Q63627 1048 113683 N645 P F W G P G F N P M H L P P G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001012840 1092 120824 P736 P P P P I T P P V S V P H T P
Frog Xenopus laevis NP_001089259 1271 143182 A908 E N V Q A R N A D D D H E P Q
Zebra Danio Brachydanio rerio XP_695887 1070 118687 A670 P G F L P P G A M P H M G A A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001097394 1306 140737 G757 G A P F P P P G A V P P P I P
Honey Bee Apis mellifera XP_392804 1292 145445 A750 G P M G L P M A H S L M P N V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784032 1759 192667 P1004 I M N P G M M P G Q R M P P P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 36.3 97.8 38.9 N.A. 85.4 65.6 N.A. N.A. 78.9 35.9 49 N.A. 31.6 29.5 N.A. 30
Protein Similarity: 100 49.2 98.1 51.2 N.A. 88.5 72 N.A. N.A. 84.3 48.3 61.4 N.A. 44 43.3 N.A. 41.9
P-Site Identity: 100 53.3 100 53.3 N.A. 100 13.3 N.A. N.A. 40 0 26.6 N.A. 33.3 13.3 N.A. 6.6
P-Site Similarity: 100 60 100 60 N.A. 100 20 N.A. N.A. 46.6 13.3 40 N.A. 33.3 33.3 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 0 9 0 0 25 9 0 0 0 9 9 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 9 9 9 0 0 0 0 % D
% Glu: 9 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % E
% Phe: 0 9 9 9 0 0 9 0 0 0 0 0 0 0 0 % F
% Gly: 17 9 0 17 9 9 9 9 9 0 0 0 9 0 9 % G
% His: 0 0 0 0 0 0 0 0 9 0 17 9 34 0 0 % H
% Ile: 9 0 25 0 9 0 0 0 25 0 0 0 0 25 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 9 9 0 0 0 0 0 9 9 0 0 0 % L
% Met: 0 9 9 0 0 9 17 0 9 9 0 25 0 0 0 % M
% Asn: 0 9 9 0 0 0 9 9 0 0 0 0 0 9 0 % N
% Pro: 67 59 34 17 67 67 34 17 9 50 50 59 34 25 67 % P
% Gln: 0 0 0 9 0 0 0 0 0 9 0 0 0 0 9 % Q
% Arg: 0 0 0 0 0 9 0 0 0 0 9 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 25 0 17 0 0 0 0 0 % S
% Thr: 0 0 0 25 0 9 0 0 0 0 0 0 9 34 0 % T
% Val: 0 0 9 17 0 0 25 17 25 9 9 0 0 0 9 % V
% Trp: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _