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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SFRS15
All Species:
20
Human Site:
Y592
Identified Species:
40
UniProt:
O95104
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95104
NP_001138916.1
1147
125869
Y592
I
K
A
D
Y
K
Q
Y
W
D
V
E
L
G
V
Chimpanzee
Pan troglodytes
XP_527544
1370
151436
F660
V
K
T
E
Y
K
Q
F
W
D
V
D
L
G
V
Rhesus Macaque
Macaca mulatta
XP_001097324
1153
126789
Y590
I
K
A
D
Y
K
Q
Y
W
D
V
E
L
G
V
Dog
Lupus familis
XP_533458
1277
141249
F567
V
K
T
E
Y
K
Q
F
W
D
V
D
L
G
V
Cat
Felis silvestris
Mouse
Mus musculus
NP_849254
1209
131664
Y657
I
K
A
D
Y
K
Q
Y
W
D
V
E
L
G
V
Rat
Rattus norvegicus
Q63627
1048
113683
S528
V
K
A
E
E
L
E
S
F
C
E
G
G
M
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001012840
1092
120824
Y580
I
K
P
D
Y
K
Q
Y
W
D
V
E
L
G
V
Frog
Xenopus laevis
NP_001089259
1271
143182
F559
V
K
T
E
Y
K
Q
F
W
D
V
D
L
G
V
Zebra Danio
Brachydanio rerio
XP_695887
1070
118687
Y542
I
K
A
E
F
K
Q
Y
W
D
V
E
L
G
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001097394
1306
140737
W576
S
K
E
W
K
D
Y
W
D
L
E
L
G
V
T
Honey Bee
Apis mellifera
XP_392804
1292
145445
W595
G
K
E
W
K
D
Y
W
E
V
E
L
G
V
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784032
1759
192667
R530
S
T
T
L
W
L
G
R
L
A
K
S
I
A
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
36.3
97.8
38.9
N.A.
85.4
65.6
N.A.
N.A.
78.9
35.9
49
N.A.
31.6
29.5
N.A.
30
Protein Similarity:
100
49.2
98.1
51.2
N.A.
88.5
72
N.A.
N.A.
84.3
48.3
61.4
N.A.
44
43.3
N.A.
41.9
P-Site Identity:
100
66.6
100
66.6
N.A.
100
13.3
N.A.
N.A.
93.3
66.6
86.6
N.A.
6.6
6.6
N.A.
0
P-Site Similarity:
100
93.3
100
93.3
N.A.
100
46.6
N.A.
N.A.
93.3
93.3
100
N.A.
13.3
13.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
42
0
0
0
0
0
0
9
0
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% C
% Asp:
0
0
0
34
0
17
0
0
9
67
0
25
0
0
0
% D
% Glu:
0
0
17
42
9
0
9
0
9
0
25
42
0
0
9
% E
% Phe:
0
0
0
0
9
0
0
25
9
0
0
0
0
0
0
% F
% Gly:
9
0
0
0
0
0
9
0
0
0
0
9
25
67
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
42
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% I
% Lys:
0
92
0
0
17
67
0
0
0
0
9
0
0
0
0
% K
% Leu:
0
0
0
9
0
17
0
0
9
9
0
17
67
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
67
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% R
% Ser:
17
0
0
0
0
0
0
9
0
0
0
9
0
0
9
% S
% Thr:
0
9
34
0
0
0
0
0
0
0
0
0
0
0
9
% T
% Val:
34
0
0
0
0
0
0
0
0
9
67
0
0
17
67
% V
% Trp:
0
0
0
17
9
0
0
17
67
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
59
0
17
42
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _