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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
S1PR2
All Species:
14.24
Human Site:
T345
Identified Species:
31.33
UniProt:
O95136
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95136
NP_004221.3
353
38867
T345
M
H
M
P
T
S
P
T
F
L
E
G
N
T
V
Chimpanzee
Pan troglodytes
XP_513598
382
42768
E370
K
D
D
G
D
N
P
E
T
I
M
S
S
G
N
Rhesus Macaque
Macaca mulatta
XP_001100481
353
38892
T345
M
H
M
P
T
S
P
T
F
L
E
G
N
T
V
Dog
Lupus familis
XP_542076
352
38638
M344
T
H
M
P
T
S
P
M
F
L
E
D
N
T
I
Cat
Felis silvestris
Mouse
Mus musculus
P52592
352
38853
T344
M
H
M
P
T
S
P
T
F
L
E
G
N
T
V
Rat
Rattus norvegicus
P47752
352
38716
T344
L
H
M
P
T
S
P
T
F
L
E
G
N
T
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520197
378
41947
E366
K
D
E
G
D
C
P
E
T
I
M
S
S
G
N
Chicken
Gallus gallus
XP_428818
380
42633
Q350
K
S
S
S
S
N
T
Q
K
P
K
D
D
F
P
Frog
Xenopus laevis
Q9PU17
366
41345
V358
N
H
T
I
L
A
G
V
H
S
N
D
H
S
V
Zebra Danio
Brachydanio rerio
Q9I8K8
370
41758
S359
T
N
K
H
E
H
Q
S
I
P
I
M
Q
D
C
Tiger Blowfish
Takifugu rubipres
Q9PUQ8
384
42694
A349
S
Q
Q
S
S
R
P
A
E
L
D
R
E
Q
E
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
45.8
98.5
89.5
N.A.
90.3
90
N.A.
44.9
41.8
34.9
55.6
44.2
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
63.8
99.1
93.1
N.A.
93.7
93.7
N.A.
61.3
60.2
55.4
71.3
61.4
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
100
73.3
N.A.
100
93.3
N.A.
6.6
0
13.3
0
13.3
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
100
80
N.A.
100
100
N.A.
20
26.6
33.3
13.3
26.6
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
0
10
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
10
% C
% Asp:
0
19
10
0
19
0
0
0
0
0
10
28
10
10
0
% D
% Glu:
0
0
10
0
10
0
0
19
10
0
46
0
10
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
46
0
0
0
0
10
0
% F
% Gly:
0
0
0
19
0
0
10
0
0
0
0
37
0
19
0
% G
% His:
0
55
0
10
0
10
0
0
10
0
0
0
10
0
0
% H
% Ile:
0
0
0
10
0
0
0
0
10
19
10
0
0
0
10
% I
% Lys:
28
0
10
0
0
0
0
0
10
0
10
0
0
0
0
% K
% Leu:
10
0
0
0
10
0
0
0
0
55
0
0
0
0
0
% L
% Met:
28
0
46
0
0
0
0
10
0
0
19
10
0
0
0
% M
% Asn:
10
10
0
0
0
19
0
0
0
0
10
0
46
0
19
% N
% Pro:
0
0
0
46
0
0
73
0
0
19
0
0
0
0
10
% P
% Gln:
0
10
10
0
0
0
10
10
0
0
0
0
10
10
0
% Q
% Arg:
0
0
0
0
0
10
0
0
0
0
0
10
0
0
0
% R
% Ser:
10
10
10
19
19
46
0
10
0
10
0
19
19
10
0
% S
% Thr:
19
0
10
0
46
0
10
37
19
0
0
0
0
46
0
% T
% Val:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
46
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _