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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: S1PR2 All Species: 26.36
Human Site: Y20 Identified Species: 58
UniProt: O95136 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95136 NP_004221.3 353 38867 Y20 K V Q E H Y N Y T K E T L E T
Chimpanzee Pan troglodytes XP_513598 382 42768 Y31 I I V R H Y N Y T G K L N I S
Rhesus Macaque Macaca mulatta XP_001100481 353 38892 Y20 K V Q E H Y N Y T K E T L E T
Dog Lupus familis XP_542076 352 38638 Y20 K V R E H Y N Y T K E T L D T
Cat Felis silvestris
Mouse Mus musculus P52592 352 38853 Y20 K V L E H Y N Y T K E T L D M
Rat Rattus norvegicus P47752 352 38716 Y20 K V Q E H Y N Y T K E T L D M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520197 378 41947 Y29 I I I R H Y N Y T G K L N P G
Chicken Gallus gallus XP_428818 380 42633 T31 I V L H Y N Y T G K L I L R E
Frog Xenopus laevis Q9PU17 366 41345 R38 T I A F F Y N R S G K Y L A T
Zebra Danio Brachydanio rerio Q9I8K8 370 41758 Y22 T M S K Y S Q Y F N K T L I Q
Tiger Blowfish Takifugu rubipres Q9PUQ8 384 42694 T22 G K L D H R P T V G T S P G T
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 45.8 98.5 89.5 N.A. 90.3 90 N.A. 44.9 41.8 34.9 55.6 44.2 N.A. N.A. N.A. N.A.
Protein Similarity: 100 63.8 99.1 93.1 N.A. 93.7 93.7 N.A. 61.3 60.2 55.4 71.3 61.4 N.A. N.A. N.A. N.A.
P-Site Identity: 100 33.3 100 86.6 N.A. 80 86.6 N.A. 33.3 20 26.6 20 13.3 N.A. N.A. N.A. N.A.
P-Site Similarity: 100 53.3 100 100 N.A. 86.6 93.3 N.A. 46.6 26.6 46.6 46.6 26.6 N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 0 0 0 0 0 0 0 0 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 10 0 0 0 0 0 0 0 0 0 28 0 % D
% Glu: 0 0 0 46 0 0 0 0 0 0 46 0 0 19 10 % E
% Phe: 0 0 0 10 10 0 0 0 10 0 0 0 0 0 0 % F
% Gly: 10 0 0 0 0 0 0 0 10 37 0 0 0 10 10 % G
% His: 0 0 0 10 73 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 28 28 10 0 0 0 0 0 0 0 0 10 0 19 0 % I
% Lys: 46 10 0 10 0 0 0 0 0 55 37 0 0 0 0 % K
% Leu: 0 0 28 0 0 0 0 0 0 0 10 19 73 0 0 % L
% Met: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 19 % M
% Asn: 0 0 0 0 0 10 73 0 0 10 0 0 19 0 0 % N
% Pro: 0 0 0 0 0 0 10 0 0 0 0 0 10 10 0 % P
% Gln: 0 0 28 0 0 0 10 0 0 0 0 0 0 0 10 % Q
% Arg: 0 0 10 19 0 10 0 10 0 0 0 0 0 10 0 % R
% Ser: 0 0 10 0 0 10 0 0 10 0 0 10 0 0 10 % S
% Thr: 19 0 0 0 0 0 0 19 64 0 10 55 0 0 46 % T
% Val: 0 55 10 0 0 0 0 0 10 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 19 73 10 73 0 0 0 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _