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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SNUPN All Species: 6.36
Human Site: S270 Identified Species: 9.33
UniProt: O95149 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95149 NP_001036046.1 360 41143 S270 Q T H Y S P G S T P L V G W L
Chimpanzee Pan troglodytes XP_001137461 134 14961 L47 Y S P G S T P L V G W L R P Y
Rhesus Macaque Macaca mulatta XP_001101744 101 11846 V14 A L A S S F S V S Q D L N S T
Dog Lupus familis XP_544780 358 41018 G271 K Q T H Y S P G S T P L V G W
Cat Felis silvestris
Mouse Mus musculus Q80W37 358 41014 G271 K Q T H Y S P G S T P L V G W
Rat Rattus norvegicus Q68FP5 358 40946 G271 K Q T H Y S P G S T P L V G W
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519445 259 29034 P172 H Y S P G S T P L V G W L R P
Chicken Gallus gallus Q5ZI43 365 40723 S273 Q T H Y T P G S T P L V G W L
Frog Xenopus laevis NP_001079462 343 39131 F256 Q G V L M Q E F S Y K V D G F
Zebra Danio Brachydanio rerio NP_955988 365 41581 T276 L L F Y H K E T H Y T P G S T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001137877 351 41485 K264 L P V N K C Y K A P E D Y Q P
Honey Bee Apis mellifera XP_623679 342 39933 S255 C D T D I S L S L A N L P N L
Nematode Worm Caenorhab. elegans NP_493639 322 37004 Q235 I P S C P C S Q D Q M A E L M
Sea Urchin Strong. purpuratus XP_798268 321 35953 P234 P P S S T P S P A K P D K K G
Poplar Tree Populus trichocarpa XP_002321701 420 47533 N273 H A H Y Q T G N T P L A L V W
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_567711 417 46953 N271 H A H Y H T G N T P L V L I W
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 37.2 27.5 91.1 N.A. 92.2 91.6 N.A. 58.3 69 68.6 65.2 N.A. 33 35 37.2 38
Protein Similarity: 100 37.2 28 95.5 N.A. 95.8 95.8 N.A. 62.2 81 80 80.5 N.A. 48.3 53.8 53 53
P-Site Identity: 100 6.6 6.6 0 N.A. 0 0 N.A. 0 93.3 13.3 13.3 N.A. 6.6 13.3 0 6.6
P-Site Similarity: 100 20 20 26.6 N.A. 26.6 26.6 N.A. 0 100 20 20 N.A. 6.6 20 13.3 13.3
Percent
Protein Identity: 26.6 N.A. N.A. 28.7 N.A. N.A.
Protein Similarity: 45.4 N.A. N.A. 47.7 N.A. N.A.
P-Site Identity: 40 N.A. N.A. 46.6 N.A. N.A.
P-Site Similarity: 46.6 N.A. N.A. 53.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 13 7 0 0 0 0 0 13 7 0 13 0 0 0 % A
% Cys: 7 0 0 7 0 13 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 7 0 7 0 0 0 0 7 0 7 13 7 0 0 % D
% Glu: 0 0 0 0 0 0 13 0 0 0 7 0 7 0 0 % E
% Phe: 0 0 7 0 0 7 0 7 0 0 0 0 0 0 7 % F
% Gly: 0 7 0 7 7 0 25 19 0 7 7 0 19 25 7 % G
% His: 19 0 25 19 13 0 0 0 7 0 0 0 0 0 0 % H
% Ile: 7 0 0 0 7 0 0 0 0 0 0 0 0 7 0 % I
% Lys: 19 0 0 0 7 7 0 7 0 7 7 0 7 7 0 % K
% Leu: 13 13 0 7 0 0 7 7 13 0 25 38 19 7 19 % L
% Met: 0 0 0 0 7 0 0 0 0 0 7 0 0 0 7 % M
% Asn: 0 0 0 7 0 0 0 13 0 0 7 0 7 7 0 % N
% Pro: 7 19 7 7 7 19 25 13 0 32 25 7 7 7 13 % P
% Gln: 19 19 0 0 7 7 0 7 0 13 0 0 0 7 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 7 7 0 % R
% Ser: 0 7 19 13 19 32 19 19 32 0 0 0 0 13 0 % S
% Thr: 0 13 25 0 13 19 7 7 25 19 7 0 0 0 13 % T
% Val: 0 0 13 0 0 0 0 7 7 7 0 25 19 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 7 7 0 13 32 % W
% Tyr: 7 7 0 32 19 0 7 0 0 13 0 0 7 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _